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Gene Information

Gene symbol: LAMC2

Gene name: laminin, gamma 2

HGNC ID: 6493

Synonyms: nicein-100kDa, kalinin-105kDa, BM600-100kDa

Related Genes

#	Gene Symbol	Number of hits
1	CHPT1	1 hits
2	DIAPH1	1 hits
3	FSTL1	1 hits
4	ITGA3	1 hits
5	LEP	1 hits
6	MIRN198	1 hits
7	NID1	1 hits
8	NID2	1 hits
9	PLAU	1 hits
10	TPO	1 hits
11	WARS	1 hits

Related Sentences

#	PMID	Sentence
1	8625929	From our results, we hypothesize that the binding of leptin to its site may cause the release or transport of uncharacterized factor(s) into the cerebral spinal fluid (CSF) to affect neuronal populations controlling feeding and metabolism.
2	15648714	Common features are high anti-thyroid peroxidase antibody titres, an abnormal EEG and an elevated CSF protein concentration.
3	19828126	Our previous data suggested the involvement of matrix metalloproteinase-10 (MMP-10) and cathepsin F (CTSF) in the basement membrane and integrin changes occurring in diabetic corneas.
4	19828126	These markers were now examined in normal human organ-cultured corneas upon recombinant adenovirus (rAV)-driven transduction of MMP-10 and CTSF genes.
5	19828126	One cornea of each pair was transduced with rAV expressing either CTSF or MMP-10 genes. 1-2 x 10(8) plaque forming units of rAV per cornea were added to cultures for 48 h with or without sildenafil citrate.
6	19828126	Corneas transduced with CTSF or MMP-10 genes or their combination had increased epithelial immunostaining of respective proteins compared to fellow control corneas.
7	19828126	Staining for diabetic markers integrin alpha(3)beta(1), nidogen-1, nidogen-2, and laminin gamma2 chain became weaker and irregular upon proteinase transduction.
8	19828126	The data suggest that MMP-10 and CTSF may be responsible for abnormal marker patterns and impaired wound healing in diabetic corneas.
9	23395958	'See-saw' expression of microRNA-198 and FSTL1 from a single transcript in wound healing.
10	23395958	Expression of primate-specific exonic microRNA-198 (miR-198), located in the 3'-untranslated region of follistatin-like 1 (FSTL1) messenger RNA, switches to expression of the linked open reading frame of FSTL1 upon wounding in a human ex vivo organ culture system.
11	23395958	We show that binding of a KH-type splicing regulatory protein (KSRP, also known as KHSRP) to the primary transcript determines the fate of the transcript and is essential for the processing of miR-198: transforming growth factor-β signalling switches off miR-198 expression by downregulating KSRP, and promotes FSTL1 protein expression.
12	23395958	We also show that FSTL1 expression promotes keratinocyte migration, whereas miR-198 expression has the opposite effect by targeting and inhibiting DIAPH1, PLAU and LAMC2.
13	23395958	A clear inverse correlation between the expression pattern of FSTL1 (pro-migratory) and miR-198 (anti-migratory) highlights the importance of this regulatory switch in controlling context-specific gene expression to orchestrate wound re-epithelialization.
14	23395958	The deleterious effect of failure of this switch is apparent in non-healing chronic diabetic ulcers, in which expression of miR-198 persists, FSTL1 is absent, and keratinocyte migration, re-epithelialization and wound healing all fail to occur.
15	23614970	Mean CPT and CSF were 186.6 ± 28.4 and 215.2 ± 25 µm, respectively, significantly increased compared to healthy subjects (p < 0.001).
16	23614970	CPT and CSF thickness were significantly thicker in men.
17	23614970	Mean CPT and CSF were 186.6 ± 28.4 and 215.2 ± 25 µm, respectively, significantly increased compared to healthy subjects (p < 0.001).
18	23614970	CPT and CSF thickness were significantly thicker in men.