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Gene Information
Gene symbol: LEO1
Gene name: Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
HGNC ID: 30401
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CDC73 | 1 hits |
| 2 | PAF1 | 1 hits |
| 3 | PXMP3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17314275 | Human parafibromin binds to RNA polymerase II as part of a PAF1 transcriptional regulatory complex. |
| 2 | 17314275 | Because the subcellular localization of parafibromin is likely to be critical for its function with the nuclear PAF1 complex, we sought to experimentally define the nuclear localization signal (NLS) of parafibromin and examine its potential role in parafibromin function. |
| 3 | 17314275 | The NLS-mutant parafibromin is significantly impaired in its association with endogenous Paf1 and Leo1. |
| 4 | 17314275 | Inhibition of endogenous parafibromin expression by RNA interference inhibits the basal rate of apoptosis and apoptosis resulting from DNA damage induced by camptothecin, a topoisomerase I inhibitor. |