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Gene Information
Gene symbol: LPAR4
Gene name: lysophosphatidic acid receptor 4
HGNC ID: 4478
Synonyms: P2Y9, P2Y5-LIKE, P2RY9, LPA4
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | LPA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17149545 | We then examined insulin signaling pathway where palmitate significantly inhibited insulin stimulated phosphorylation of Insulin receptor tyrosine kinase, IRS 1and PI3 kinase, PDK1 and Akt/PKB. |
| 2 | 17149545 | LPA(4) rescued this inhibition of signaling molecule by palmitate. |
| 3 | 17149545 | Insulin mediated translocation of Glut4, the glucose transporter in insulin target cells, was effectively blocked by palmitate while, LPA(4) waived this block. |
| 4 | 17149545 | Administration of LPA(4) to nutritionally induced diabetic rats significantly reduced the increase in plasma glucose. |
| 5 | 17149545 | All these indicate LPA(4) to be a potentially therapeutic agent for insulin resistance and type 2 diabetes. |
| 6 | 17149545 | We then examined insulin signaling pathway where palmitate significantly inhibited insulin stimulated phosphorylation of Insulin receptor tyrosine kinase, IRS 1and PI3 kinase, PDK1 and Akt/PKB. |
| 7 | 17149545 | LPA(4) rescued this inhibition of signaling molecule by palmitate. |
| 8 | 17149545 | Insulin mediated translocation of Glut4, the glucose transporter in insulin target cells, was effectively blocked by palmitate while, LPA(4) waived this block. |
| 9 | 17149545 | Administration of LPA(4) to nutritionally induced diabetic rats significantly reduced the increase in plasma glucose. |
| 10 | 17149545 | All these indicate LPA(4) to be a potentially therapeutic agent for insulin resistance and type 2 diabetes. |
| 11 | 17149545 | We then examined insulin signaling pathway where palmitate significantly inhibited insulin stimulated phosphorylation of Insulin receptor tyrosine kinase, IRS 1and PI3 kinase, PDK1 and Akt/PKB. |
| 12 | 17149545 | LPA(4) rescued this inhibition of signaling molecule by palmitate. |
| 13 | 17149545 | Insulin mediated translocation of Glut4, the glucose transporter in insulin target cells, was effectively blocked by palmitate while, LPA(4) waived this block. |
| 14 | 17149545 | Administration of LPA(4) to nutritionally induced diabetic rats significantly reduced the increase in plasma glucose. |
| 15 | 17149545 | All these indicate LPA(4) to be a potentially therapeutic agent for insulin resistance and type 2 diabetes. |