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Gene Information
Gene symbol: LRSAM1
Gene name: leucine rich repeat and sterile alpha motif containing 1
HGNC ID: 25135
Synonyms: FLJ31641
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | TRHR | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 23087672 | Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor. |
| 2 | 23087672 | In this study, we characterized TAL binding to and signaling by the human TRH receptor (TRH-R) in a model cell system. |
| 3 | 23087672 | We found that TAL exhibited lower binding affinities than TRH and lower signaling potency via the inositol-1,4,5-trisphosphate/calcium pathway than TRH. |
| 4 | 23087672 | However, TAL exhibited higher intrinsic efficacy than TRH in stimulating inositol-1,4,5-trisphosphate second messenger generation. |
| 5 | 23087672 | This is the first study that elucidates the pharmacology of TAL at TRH-R and shows that TAL is a superagonist at TRH-R. |