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Gene Information

Gene symbol: MBD3

Gene name: methyl-CpG binding domain protein 3

HGNC ID: 6918

Related Genes

# Gene Symbol Number of hits
1 DNMT1 1 hits
2 DNMT3L 1 hits
3 ZFP57 1 hits

Related Sentences

# PMID Sentence
1 20738330 Silver-Russell patients showing a broad range of ICR1 and ICR2 hypomethylation in different tissues.
2 20738330 However, several patients with transient neonatal diabetes mellitus (TNDM), Silver-Russell syndrome (SRS) and Beckwith-Wiedemann syndrome (BWS) exhibiting multilocus hypomethylation (MLH) have meanwhile been described.
3 20738330 Whereas TNDM patients with MLH show clinical symptoms different from carriers with isolated 6q24 aberrations, MLH carriers diagnosed as BWS or SRS present only the syndrome-specific features.
4 20738330 Interestingly, SRS and BWS patients with nearly identical MLH patterns in leukocytes have been identified.
5 20738330 Despite mutation screening of several factors involved in establishment and maintenance of methylation marks including ZFP57, MBD3, DNMT1 and DNMT3L the molecular clue for the ICR1/ICR2 hypomethylation in our patients remained unclear.