About

Home

Introduction

Statistics

Programs

Dignet

Gene

GenePair

BioSummarAI

Help & Docs

Documents

Help

FAQs

Links

Acknowledge

Disclaimer

Contact Us

Gene Information

Gene symbol: MBNL1

Gene name: muscleblind-like splicing regulator 1

HGNC ID: 6923

Synonyms: KIAA0428, EXP42, EXP40, EXP35, EXP

Related Genes

#	Gene Symbol	Number of hits
1	COL9A3	1 hits
2	UBXD5	1 hits

Related Sentences

#	PMID	Sentence
1	14681545	In previous minireviews in this journal, we discussed work on induction of tetrahydrobiopterin biosynthesis by cytokines and its significance for nitric oxide (NO) production of intact cells as well as functions of H4-biopterin identified at this time for NO synthases (Proc Soc Exp Biol Med 203: 1-12, 1993; Proc Soc Exp Biol Med 219: 171-182, 1998).
2	22465205	Insulin-like growth factors (IGFs) are well-known regulators of embryonic growth and differentiation.
3	22465205	In rabbit blastocysts, embryonic IGF1 and IGF2 are specifically strong in the embryoblast (ICM).
4	22465205	Signalling of IGFs and insulin in blastocysts follows the classical pathway with Erk1/2 and Akt kinase activation.
5	22465205	Exp IDD was induced in female rabbits by alloxan treatment prior to mating.
6	22465205	In pregnant females, hepatic IGF1 expression and IGF1 serum levels were decreased while IGF1 and IGF2 were increased in endometrium.
7	22465205	In cultured control blastocysts supplemented with IGF1 or insulin in vitro for 1 or 12 h, IGF1 and insulin receptors as well as IGF1 and IGF2 were downregulated.
8	22465205	In cultured T1D blastocysts activation of Akt and Erk1/2 was impaired with lower amounts of total Akt and Erk1/2 protein and a reduced phosphorylation capacity after IGF1 supplementation.
9	22465205	Both, the endometrium and the blastocyst produce more IGF1 and IGF2.
10	22465205	The increased endogenous IGF1 and IGF2 expression by the blastocyst compensates for the loss of systemic insulin and IGF.