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Gene Information
Gene symbol: METAP2
Gene name: methionyl aminopeptidase 2
HGNC ID: 16672
Synonyms: MNPEP, p67, MAP2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD34 | 1 hits |
| 2 | MAPK1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21937698 | Inhibition of MetAP2 in CB CD34(+) cells by fumagillin had no effect on overall clonogenic activity but significantly reduced their engraftment into immunodeficient nonobese diabetes/severe combined immunodeficiency mice. metap2 knock-down in zebrafish and inhibition by fumagillin in zebrafish and human CB CD34(+) cells inhibited Calmodulin Kinase II activity and induced ERK phosphorylation. |
| 2 | 21937698 | This study demonstrated a hitherto-undescribed role of MetAP2 in definitive hematopoiesis and a possible link to noncanonical Wnt and ERK signaling. |
| 3 | 21937698 | Inhibition of MetAP2 in CB CD34(+) cells by fumagillin had no effect on overall clonogenic activity but significantly reduced their engraftment into immunodeficient nonobese diabetes/severe combined immunodeficiency mice. metap2 knock-down in zebrafish and inhibition by fumagillin in zebrafish and human CB CD34(+) cells inhibited Calmodulin Kinase II activity and induced ERK phosphorylation. |
| 4 | 21937698 | This study demonstrated a hitherto-undescribed role of MetAP2 in definitive hematopoiesis and a possible link to noncanonical Wnt and ERK signaling. |