Ignet

Gene Information

Gene symbol: MLLT3

Gene name: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

HGNC ID: 7136

Synonyms: AF-9, AF9, YEATS3

Related Genes

#	Gene Symbol	Number of hits
1	AAVS1	1 hits
2	ACTB	1 hits
3	BRCA1	1 hits
4	BRD4	1 hits
5	BRPF1	1 hits
6	CD44	1 hits
7	CDKN1C	1 hits
8	CSF1	1 hits
9	DDIT3	1 hits
10	DYNC1H1	1 hits
11	FOS	1 hits
12	GPR180	1 hits
13	HIST1H2BO	1 hits
14	HIST2H2BE	1 hits
15	HSPG2	1 hits
16	IGF1	1 hits
17	IGFALS	1 hits
18	IGFBP2	1 hits
19	IL2	1 hits
20	INS	1 hits
21	MDK	1 hits
22	RARA	1 hits
23	SLC9A3R2	1 hits
24	SMARCA1	1 hits
25	TCEB1	1 hits
26	TP63	1 hits

Related Sentences

#	PMID	Sentence
1	9032395	The Rep proteins of adeno-associated virus type 2 (AAV) are known to bind to Rep recognition sequences (RRSs) in the AAV inverted terminal repeats (ITRs), the AAV p5 promoter, and the preferred AAV integration site in human chromosome 19, called AAVS1.
2	9032395	We used the 16-mer core sequences of the RRSs in the AAV ITRs and AAVS1 separately as query sequences and identified 18 new RRSs in or flanking the genes coding for the following: tyrosine kinase activator protein 1 (TKA-1); colony stimulating factor-1; insulin-like growth factor binding protein 2 (IGFBP-2); histone H2B.1; basement membrane heparan sulfate proteoglycan, also known as perlecan; the AF-9 gene product, which is involved in the chromosomal translocation t (9:11)(p22:q23); the betaB subunit of the hormone known as inhibin; interleukin-2 enhancer binding factor; an endoplasmic reticulum-Golgi intermediate compartment resident protein called p63; a global transcription activator (hSNF2L); the beta-actin repair domain; a retinoic acid-inducible factor, also known as midkine; a breast tumor autoantigen; a growth-arrest- and DNA-damage-inducible protein called gadd45; the cyclin-dependent kinase inhibitor called KIP2, which inhibits several G1 cyclin-cyclin-dependent kinase complexes; and the hereditary breast and ovarian cancer gene (BRCA1).
3	23762261	The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors.
4	23762261	Indeed, mass spectrometry fingerprinting identified the Bromodomain-containing protein 4 (BRD4) and ALL1-fused gene from chromosome 9 (AF9/MLLT3), known to associate with and regulates the activity of Positive Transcription Elongation Factor b (P-TEFb), as novel RAR coactivators.
5	23762261	Knockdown of either AF9 or BRD4 expression affected differentially the neural differentiation of stem cell-like P19 cells.
6	23762261	Clusters of retinoid-regulated genes were selectively dependent on BRD4 and/or AF9 expression, which correlated with RAR association to transcribed regions.
7	23762261	The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors.
8	23762261	Indeed, mass spectrometry fingerprinting identified the Bromodomain-containing protein 4 (BRD4) and ALL1-fused gene from chromosome 9 (AF9/MLLT3), known to associate with and regulates the activity of Positive Transcription Elongation Factor b (P-TEFb), as novel RAR coactivators.
9	23762261	Knockdown of either AF9 or BRD4 expression affected differentially the neural differentiation of stem cell-like P19 cells.
10	23762261	Clusters of retinoid-regulated genes were selectively dependent on BRD4 and/or AF9 expression, which correlated with RAR association to transcribed regions.
11	23762261	The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors.
12	23762261	Indeed, mass spectrometry fingerprinting identified the Bromodomain-containing protein 4 (BRD4) and ALL1-fused gene from chromosome 9 (AF9/MLLT3), known to associate with and regulates the activity of Positive Transcription Elongation Factor b (P-TEFb), as novel RAR coactivators.
13	23762261	Knockdown of either AF9 or BRD4 expression affected differentially the neural differentiation of stem cell-like P19 cells.
14	23762261	Clusters of retinoid-regulated genes were selectively dependent on BRD4 and/or AF9 expression, which correlated with RAR association to transcribed regions.
15	23762261	The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors.
16	23762261	Indeed, mass spectrometry fingerprinting identified the Bromodomain-containing protein 4 (BRD4) and ALL1-fused gene from chromosome 9 (AF9/MLLT3), known to associate with and regulates the activity of Positive Transcription Elongation Factor b (P-TEFb), as novel RAR coactivators.
17	23762261	Knockdown of either AF9 or BRD4 expression affected differentially the neural differentiation of stem cell-like P19 cells.
18	23762261	Clusters of retinoid-regulated genes were selectively dependent on BRD4 and/or AF9 expression, which correlated with RAR association to transcribed regions.