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Gene Information
Gene symbol: MRRF
Gene name: mitochondrial ribosome recycling factor
HGNC ID: 7234
Synonyms: RRF
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | COX8A | 1 hits |
| 2 | COX8B | 1 hits |
| 3 | MELAS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 7643139 | Finally, in contrast with other mtDNA mutations associated with ragged-red fibres (RRF), in both MELAS3243 and CPEO3243 we observed a high proportion of RRF that were positive to the histochemical reaction to cytochrome c oxidase, a morphological feature that seems to be specific for the neuromuscular phenotypes associated with mutations affecting the tRNA(Leu(UUR)) gene. |
| 2 | 9741403 | On the other hand, the proportion of mutant DNA in non-RRF revealed a wider range than in RRF and the average was higher in MELAS patients (58.5+/-27.3%) than that in MDM patients (26.3+/-27.9%), which correlated with biochemical and morphological mitochondrial abnormalities in muscle. |
| 3 | 15607216 | Muscle biopsy showed about 12% cytochrome c oxidase (COX)-negative ragged-red fibers (RRFs), and markedly decreased activities of mitochondrial respiratory chain complexes I, III and IV. |
| 4 | 15607216 | Muscle biopsy showed focal COX-negative RRFs and decreased activities of complexes I, III and IV. |
| 5 | 15607216 | Muscle biopsy showed about 12% cytochrome c oxidase (COX)-negative ragged-red fibers (RRFs), and markedly decreased activities of mitochondrial respiratory chain complexes I, III and IV. |
| 6 | 15607216 | Muscle biopsy showed focal COX-negative RRFs and decreased activities of complexes I, III and IV. |