# |
PMID |
Sentence |
1 |
2236064
|
Outside of this segment of approximately 330 amino acids, the structures of the p70 and p85 S6 kinases diverge substantially.
|
2 |
2236064
|
The p70 S6 kinase is known to be activated through serine/threonine phosphorylation by unidentified insulin/mitogen-activated protein kinases.
|
3 |
2236064
|
This motif may prevent autophosphorylation but permit transphosphorylation; two of these serine residues reside in a maturation promoting factor (MPF)/cdc-2 consensus motif.
|
4 |
2236064
|
Thus, hormonal regulation of S6 kinase may involve the action of MPF/cdc-2 or protein kinases with related substrate specificity.
|
5 |
2236064
|
Outside of this segment of approximately 330 amino acids, the structures of the p70 and p85 S6 kinases diverge substantially.
|
6 |
2236064
|
The p70 S6 kinase is known to be activated through serine/threonine phosphorylation by unidentified insulin/mitogen-activated protein kinases.
|
7 |
2236064
|
This motif may prevent autophosphorylation but permit transphosphorylation; two of these serine residues reside in a maturation promoting factor (MPF)/cdc-2 consensus motif.
|
8 |
2236064
|
Thus, hormonal regulation of S6 kinase may involve the action of MPF/cdc-2 or protein kinases with related substrate specificity.
|