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Gene Information
Gene symbol: MUC5B
Gene name: mucin 5B, oligomeric mucus/gel-forming
HGNC ID: 7516
Synonyms: MG1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD59 | 1 hits |
| 2 | EDN1 | 1 hits |
| 3 | EDN3 | 1 hits |
| 4 | IL17F | 1 hits |
| 5 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 1794265 | In healthy subjects, the glucose load after placebo induced an insulin response of 7.4 +/- 1.0 and 11.3 +/- 1.4 microU ml-1 min-1 mg-1 dl-1 for the first and second phases, respectively, and an insulin sensitivity evaluated to be 4.7 +/- 0.3 min microU-1 ml-1. |
| 2 | 1794265 | In diabetic subjects the insulin response to the glucose load after placebo was markedly decreased (2.2 +/- 0.5 and 2.5 +/- 0.3 microU ml-1 min-1 mg-1 dl-1, respectively) as was the insulin sensitivity (2.5 +/- 0.3 min microU-1 ml-1). |
| 3 | 1794265 | In healthy subjects, the glucose load after placebo induced an insulin response of 7.4 +/- 1.0 and 11.3 +/- 1.4 microU ml-1 min-1 mg-1 dl-1 for the first and second phases, respectively, and an insulin sensitivity evaluated to be 4.7 +/- 0.3 min microU-1 ml-1. |
| 4 | 1794265 | In diabetic subjects the insulin response to the glucose load after placebo was markedly decreased (2.2 +/- 0.5 and 2.5 +/- 0.3 microU ml-1 min-1 mg-1 dl-1, respectively) as was the insulin sensitivity (2.5 +/- 0.3 min microU-1 ml-1). |
| 5 | 7929099 | The Km and Vmax for the substrate is 0.1 mM and 46 mumol 30 min-1 mg-1, respectively. |
| 6 | 9533832 | Scatchard transformation of saturation binding experiments revealed that the KD and Bmax for [125I]ET-1 and [125I]ET-3 to membranes from ciliary body were 41.7+/-9 pM and 236+/-20 fmol mg-1 protein and 37. 8+/-0.4 pM and 160+/-2.0 fmol mg-1 protein, respectively. |
| 7 | 9533832 | Competitive experiments in the presence of cyclic pentapeptide BQ123 (selective for ETA receptors) and BQ3020 (selective for ETB receptors), demonstrated the existence of ETA and ETB receptors in a ratio of 35:65. |
| 8 | 9533832 | Cross-linking of [125I]ET-1 and [125I]ET-3 to ciliary body membranes resulted in the labeling of two bands with apparent molecular masses of 52 and 34 kDa, suggesting that ETA and ETB receptors have similar molecular mass. |
| 9 | 9533832 | Autoradiographic results show that specific [125I]ET-1 binding sites, displaced by BQ123 and BQ3020, are localized to the ciliary epithelium, supporting the idea that ETA and ETB subtype receptors exist in this tissue. |