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Gene Information
Gene symbol: MYBL2
Gene name: v-myb myeloblastosis viral oncogene homolog (avian)-like 2
HGNC ID: 7548
Synonyms: BMYB, B-MYB
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCND1 | 1 hits |
| 2 | EGFR | 1 hits |
| 3 | HNF4A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12475768 | In addition, HNF4a and Mybl2 were screened for mutations and new polymorphisms. |
| 2 | 20406885 | It is now appreciated that in addition to signaling from the plasma membrane, EGFR also trafficks to the nucleus, and can directly bind the promoter regions of genes encoding cyclin D1 (CCND1) and B-Myb (MYBL2). |
| 3 | 20406885 | We have previously established that loss of MUC1 in an EGFR-dependent transgenic mouse model of breast cancer correlates with the loss of cyclin D1 expression. |
| 4 | 20406885 | We found that MUC1 and EGFR interact in the nucleus of breast cancer cells, which promotes the accumulation of chromatin-bound EGFR. |
| 5 | 20406885 | Importantly, we found that the loss of MUC1 expression resulted in a decrease in the interaction between EGFR and the CCND1 promoter, which translated to a significant decrease in cyclin D1 protein expression. |