Ignet

Gene Information

Gene symbol: MYCBP

Gene name: c-myc binding protein

HGNC ID: 7554

Synonyms: AMY-1

Related Genes

#	Gene Symbol	Number of hits
1	AMY1A	1 hits
2	AMY2A	1 hits
3	CALCR	1 hits
4	CD53	1 hits
5	INS	1 hits
6	OLFM1	1 hits
7	RAMP1	1 hits

Related Sentences

#	PMID	Sentence
1	7829080	Furthermore, an additional HSA1p marker, Cd53, mapped close to Amy1 on mouse chromosome 3, and a sequence related to Lap18 mapped to mouse chromosome 17, near D17Mit3.
2	7829080	This comparative approach suggests that the human counterparts of these genes may have a similar order on human chromosome 1p and also indicates that Lap18, C1qB, and Nhe1 are candidates for a recently described diabetes susceptibility gene on mouse chromosome 4.
3	11427050	The nitrogen analogues 11 and 12 showed no significant inhibitory effect of either barley alpha-amylase (AMY1) or porcine pancreatic alpha-amylase (PPA) at concentrations of 5 mM.
4	11427050	In contrast, salacinol (7) inhibited AMY1 and PPA in the micromolar range, with K(i) values of 15 +/- 1 and 10 +/- 2 microM, respectively.
5	11427050	The nitrogen analogues 11 and 12 showed no significant inhibitory effect of either barley alpha-amylase (AMY1) or porcine pancreatic alpha-amylase (PPA) at concentrations of 5 mM.
6	11427050	In contrast, salacinol (7) inhibited AMY1 and PPA in the micromolar range, with K(i) values of 15 +/- 1 and 10 +/- 2 microM, respectively.
7	20347903	Amylin (Amy) receptors are complexes of the calcitonin receptor with receptor activity-modifying proteins.
8	20347903	RAMP1 with the calcitonin receptor forms the AMY(1) receptor; the insert negative isoform of the calcitonin receptor in this complex makes the AMY(1(a)) receptor.
9	20347903	This receptor has high affinity for Amy and the related peptide calcitonin gene-related peptide (CGRP).
10	20347903	It has been suggested that the peptides bind in a pocket formed between the long N-termini of the calcitonin receptor and RAMP1, although very few residues in either component have been assigned specific roles.
11	20347903	Here, Arg67, Asp71, Glu78 and Trp84 were individually mutated to alanine and the function of mutant AMY(1(a)) receptors was determined using a cAMP assay.
12	20347903	Mutation of Arg67, Asp71 and Glu78 had no significant effect on Amy or CGRP potency, cell surface or total expression.
13	20347903	The data reveal the importance of Trp84 in the AMY(1(a)) receptor.
14	20347903	Amylin (Amy) receptors are complexes of the calcitonin receptor with receptor activity-modifying proteins.
15	20347903	RAMP1 with the calcitonin receptor forms the AMY(1) receptor; the insert negative isoform of the calcitonin receptor in this complex makes the AMY(1(a)) receptor.
16	20347903	This receptor has high affinity for Amy and the related peptide calcitonin gene-related peptide (CGRP).
17	20347903	It has been suggested that the peptides bind in a pocket formed between the long N-termini of the calcitonin receptor and RAMP1, although very few residues in either component have been assigned specific roles.
18	20347903	Here, Arg67, Asp71, Glu78 and Trp84 were individually mutated to alanine and the function of mutant AMY(1(a)) receptors was determined using a cAMP assay.
19	20347903	Mutation of Arg67, Asp71 and Glu78 had no significant effect on Amy or CGRP potency, cell surface or total expression.
20	20347903	The data reveal the importance of Trp84 in the AMY(1(a)) receptor.
21	20347903	Amylin (Amy) receptors are complexes of the calcitonin receptor with receptor activity-modifying proteins.
22	20347903	RAMP1 with the calcitonin receptor forms the AMY(1) receptor; the insert negative isoform of the calcitonin receptor in this complex makes the AMY(1(a)) receptor.
23	20347903	This receptor has high affinity for Amy and the related peptide calcitonin gene-related peptide (CGRP).
24	20347903	It has been suggested that the peptides bind in a pocket formed between the long N-termini of the calcitonin receptor and RAMP1, although very few residues in either component have been assigned specific roles.
25	20347903	Here, Arg67, Asp71, Glu78 and Trp84 were individually mutated to alanine and the function of mutant AMY(1(a)) receptors was determined using a cAMP assay.
26	20347903	Mutation of Arg67, Asp71 and Glu78 had no significant effect on Amy or CGRP potency, cell surface or total expression.
27	20347903	The data reveal the importance of Trp84 in the AMY(1(a)) receptor.
28	22492122	The samples were analyzed for plasma glucose and insulin concentrations as well as diploid AMY1 gene copy number.
29	22492122	HA individuals had significantly more AMY1 gene copies within their genomes than did the LA individuals.
30	22492122	The samples were analyzed for plasma glucose and insulin concentrations as well as diploid AMY1 gene copy number.
31	22492122	HA individuals had significantly more AMY1 gene copies within their genomes than did the LA individuals.
32	22965187	The α-amylase genes are located in a cluster on the chromosome that includes salivary amylase genes (AMY1), two pancreatic α-amylase genes (AMY2A and AMY2B) and a related pseudogene.
33	22965187	The AMY1 genes show extensive copy number variation which is directly proportional to the salivary α-amylase content in saliva.
34	22965187	It has been shown that the average copy number of AMY1 gene is higher in populations that evolved under high-starch diets versus low-starch diets, reflecting an intense positive selection imposed by diet on amylase copy number during evolution.
35	22965187	In this context, a number of different aspects can be considered in evaluating the possible impact of copy number variation of the AMY1 gene on nutrition research, such as issues related to human diet gene evolution, action on starch digestion, effect on glycemic response after starch consumption, modulation of the action of α-amylases inhibitors, effect on taste perception and satiety, influence on psychosocial stress and relation to oral health.
36	22965187	The α-amylase genes are located in a cluster on the chromosome that includes salivary amylase genes (AMY1), two pancreatic α-amylase genes (AMY2A and AMY2B) and a related pseudogene.
37	22965187	The AMY1 genes show extensive copy number variation which is directly proportional to the salivary α-amylase content in saliva.
38	22965187	It has been shown that the average copy number of AMY1 gene is higher in populations that evolved under high-starch diets versus low-starch diets, reflecting an intense positive selection imposed by diet on amylase copy number during evolution.
39	22965187	In this context, a number of different aspects can be considered in evaluating the possible impact of copy number variation of the AMY1 gene on nutrition research, such as issues related to human diet gene evolution, action on starch digestion, effect on glycemic response after starch consumption, modulation of the action of α-amylases inhibitors, effect on taste perception and satiety, influence on psychosocial stress and relation to oral health.
40	22965187	The α-amylase genes are located in a cluster on the chromosome that includes salivary amylase genes (AMY1), two pancreatic α-amylase genes (AMY2A and AMY2B) and a related pseudogene.
41	22965187	The AMY1 genes show extensive copy number variation which is directly proportional to the salivary α-amylase content in saliva.
42	22965187	It has been shown that the average copy number of AMY1 gene is higher in populations that evolved under high-starch diets versus low-starch diets, reflecting an intense positive selection imposed by diet on amylase copy number during evolution.
43	22965187	In this context, a number of different aspects can be considered in evaluating the possible impact of copy number variation of the AMY1 gene on nutrition research, such as issues related to human diet gene evolution, action on starch digestion, effect on glycemic response after starch consumption, modulation of the action of α-amylases inhibitors, effect on taste perception and satiety, influence on psychosocial stress and relation to oral health.
44	22965187	The α-amylase genes are located in a cluster on the chromosome that includes salivary amylase genes (AMY1), two pancreatic α-amylase genes (AMY2A and AMY2B) and a related pseudogene.
45	22965187	The AMY1 genes show extensive copy number variation which is directly proportional to the salivary α-amylase content in saliva.
46	22965187	It has been shown that the average copy number of AMY1 gene is higher in populations that evolved under high-starch diets versus low-starch diets, reflecting an intense positive selection imposed by diet on amylase copy number during evolution.
47	22965187	In this context, a number of different aspects can be considered in evaluating the possible impact of copy number variation of the AMY1 gene on nutrition research, such as issues related to human diet gene evolution, action on starch digestion, effect on glycemic response after starch consumption, modulation of the action of α-amylases inhibitors, effect on taste perception and satiety, influence on psychosocial stress and relation to oral health.