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Gene Information
Gene symbol: MYL2
Gene name: myosin, light chain 2, regulatory, cardiac, slow
HGNC ID: 7583
Synonyms: CMH10
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACTC1 | 1 hits |
| 2 | ATP2A1 | 1 hits |
| 3 | ATP2A2 | 1 hits |
| 4 | C12orf51 | 1 hits |
| 5 | CACNA1C | 1 hits |
| 6 | CACNA1G | 1 hits |
| 7 | CACNA1H | 1 hits |
| 8 | CACNA2D1 | 1 hits |
| 9 | CACNB2 | 1 hits |
| 10 | CALM1 | 1 hits |
| 11 | MYH14 | 1 hits |
| 12 | MYH6 | 1 hits |
| 13 | MYH7 | 1 hits |
| 14 | NPPA | 1 hits |
| 15 | OAS1 | 1 hits |
| 16 | TNNI3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8361080 | The contents of myosin heavy chain, myosin light chain 2, actin, troponin-I in 125-week-old rats decreased compared with those of 12-week-old rats. |
| 2 | 8361080 | Myosin heavy chain, which is one component of myosin, interacts with actin and changes chemical energy to mechanical energy. |
| 3 | 9217870 | This diminished calcium sensitivity along with shifts in cardiac myosin heavy chain (V1-->V3) could contribute to the impaired cardiac function in the hearts of chronic diabetic rats. |
| 4 | 9217870 | It has also been reported that sarcomeric proteins such as myosin light chain-2 (MLC-2) and troponin I (TnI) could be involved in regulating muscle contraction and in calcium sensitivity. |
| 5 | 20930262 | Our findings indicate that doxorubicin modulates the expression of the hypertrophy-associated genes, ventricular myosin light chain-2, the alpha isoform of myosin heavy chain and atrial natriuretic peptide, an effect which is augmented by Trichostatin A. |
| 6 | 21216827 | Expression of genes encoding various L-type Ca(2+) channel proteins (Cacna1c, Cacna1g, Cacna1h and Cacna2d1) and cardiac muscle proteins (Myh7) were upregulated, and genes encoding intracellular Ca(2+) transport regulatory proteins (Atp2a2 and Calm1) and some cardiac muscle proteins (Myh6, Myl2, Actc1, Tnni3, Tnn2, and Tnnc1) were downregulated in ZDF heart compared with control heart. |
| 7 | 21216827 | A change in the expression of genes encoding myosin heavy chain and L-type Ca(2+) channel proteins might partly underlie alterations in the time course of contraction and Ca(2+) transients in ventricular myocytes from ZDF rats. |
| 8 | 21666035 | Expression of genes encoding various L-type Ca(2+) channel proteins (Cacnb2) and cardiac muscle proteins (Myl2 and Atp2a1) were downregulated in GK-HFD compared with GK-LFD rats. |
| 9 | 23575436 | New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population. |
| 10 | 23575436 | Newly implicated variants (MYL2, C12orf51 and OAS1) were found to be significantly associated with 1-hPG. |
| 11 | 23575436 | New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population. |
| 12 | 23575436 | Newly implicated variants (MYL2, C12orf51 and OAS1) were found to be significantly associated with 1-hPG. |