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Gene Information
Gene symbol: MYLIP
Gene name: myosin regulatory light chain interacting protein
HGNC ID: 21155
Synonyms: MIR, IDOL
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
23372846
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Several highly-expressed islet miRNAs, such as miR-375, have established roles in the regulation of islet function, but others (e.g. miR-27b-3p, miR-192-5p) have not previously been described in the context of islet biology.
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2 |
23372846
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At six loci with genome-wide evidence for T2D association (AP3S2, KCNK16, NOTCH2, SCL30A8, VPS26A, and WFS1) predicted mRNA target sites for islet-expressed miRNAs overlapped potentially causal variants.
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3 |
23771797
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Furthermore, proteomic profiling was applied to analyze the downstream effectors involved in miR-21-meidated protection of endothelial cells.
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4 |
23771797
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A total of 31 proteins were positively identified, including Annexin A2, S100A4, SOD2, Thioredoxin and DAXX.
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5 |
23771797
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Finally, mechanistic study showed that miR-21 protected endothelial cell against high glucose-induced endothelial cytotoxicity probably by inhibiting the expression of DAXX.
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