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Gene Information
Gene symbol: MYOZ3
Gene name: myozenin 3
HGNC ID: 18565
Synonyms: CS-3, CS3, FRP3
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
15894466
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Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect.
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2 |
15894466
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To determine the underlying mechanisms of these metabolic malfunctions, we studied mitochondrial respiration, uncoupled respiration and oxidative enzyme activities (citrate synthase (CS), 3-hydroxy-acyl-CoA-dehydrogenase activity (HAD)) before and after acute exposure to insulin and/or palmitate in myotubes established from healthy lean and obese subjects and T2D patients.
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3 |
15894466
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No differences were detected in mitochondrial respiration and HAD activity between myotubes from non-diabetic subjects and T2D patients, and none of these measures responded to high levels of insulin and/or palmitate.
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