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Gene Information
Gene symbol: NKX2-3
Gene name: NK2 homeobox 3
HGNC ID: 7836
Synonyms: NKX2.3, CSX3, NKX4-3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | FOXM1 | 1 hits |
| 2 | ICOSLG | 1 hits |
| 3 | IL10 | 1 hits |
| 4 | IL12B | 1 hits |
| 5 | IL1R2 | 1 hits |
| 6 | IL23A | 1 hits |
| 7 | IL23R | 1 hits |
| 8 | JAK2 | 1 hits |
| 9 | ORMDL3 | 1 hits |
| 10 | REL | 1 hits |
| 11 | SMAD3 | 1 hits |
| 12 | STAT3 | 1 hits |
| 13 | TYK2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16075370 | The first susceptibility locus on rat Chromosome (RNO) 1 (LOD score 4.13) mapped to the region 1q51-55, which codes for potential candidate genes like Ins1 and Nkx2-3. |
| 2 | 21300624 | Amongst these are multiple genes involved in IL23/Th17 signalling (IL23R, IL12B, JAK2, TYK2 and STAT3), IL10, IL1R2, REL, CARD9, NKX2.3, ICOSLG, PRDM1, SMAD3 and ORMDL3. |
| 3 | 21300624 | For Crohn's disease, defective processing of intracellular bacteria has become a central theme, following gene discoveries in autophagy and innate immunity (associations with NOD2, IRGM, ATG16L1 are specific to Crohn's disease). |
| 4 | 21300624 | Genetic evidence has also demonstrated the importance of barrier function to the development of ulcerative colitis (HNF4A, LAMB1, CDH1 and GNA12). |