Ignet

Gene Information

Gene symbol: NOS1AP

Gene name: nitric oxide synthase 1 (neuronal) adaptor protein

HGNC ID: 16859

Synonyms: KIAA0464, CAPON

Related Genes

#	Gene Symbol	Number of hits
1	CYP1A1	1 hits
2	CYP2B6	1 hits
3	INS	1 hits
4	IRS1	1 hits
5	NOS1	1 hits
6	PPARG	1 hits
7	SLC30A8	1 hits
8	SLCO1A2	1 hits
9	TBXAS1	1 hits
10	TCF7	1 hits
11	TCF7L2	1 hits

Related Sentences

#	PMID	Sentence
1	20305679	A variation in NOS1AP gene is associated with repaglinide efficacy on insulin resistance in type 2 diabetes of Chinese.
2	23018631	These genes belong to three major classes: genes involved in drug metabolism and transporters that influence pharmacokinetics (including the cytochrome P450 [CYP] superfamily, the organic anion transporting polypeptide [OATP] family, and the polyspecific organic cation transporter [OCT] family); genes encoding drug targets and receptors (including peroxisome proliferator-activated receptor gamma [PPARG], the adenosine triphosphate [ATP]-sensitive potassium channel [K(ATP)], and incretin receptors); and genes involved in the causal pathway of T2DM that are able to modify the effects of drugs (including adipokines, transcription factor 7-like 2 (T cell specific, HMG-box) [TCF7L2], insulin receptor substrate 1 [IRS1], nitric oxide synthase 1 (neuronal) adaptor protein [NOS1AP], and solute carrier family 30 (zinc transporter), member 8 [SLC30A8]).
3	23018631	In addition to these three major classes, we also review the available evidence on novel genes (CDK5 regulatory subunit associated protein 1-like 1 [CDKAL1], insulin-like growth factor 2 mRNA binding protein 2 [IGF2BP2], potassium voltage-gated channel, KQT-like subfamily, member 1 [KCNQ1], paired box 4 [PAX4] and neuronal differentiation 1 [NEUROD1] transcription factors, ataxia telangiectasia mutated [ATM], and serine racemase [SRR]) that have recently been proposed as possible modulators of therapeutic response in subjects with T2DM.
4	23658158	The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death.
5	23658158	Excitotoxic stimulus induces recruitment of NOS1AP to nNOS in rat cortical neuron culture.
6	23658158	Excitotoxic activation of p38MAPK and subsequent neuronal death are reduced by competing with the nNOS:NOS1AP interaction and by knockdown with NOS1AP-targeting siRNAs.
7	23658158	We designed a cell-permeable peptide that competes for the unique PDZ domain of nNOS that interacts with NOS1AP.
8	23658158	This peptide inhibits NMDA-induced recruitment of NOS1AP to nNOS and in vivo in rat, doubles surviving tissue in a severe model of neonatal hypoxia-ischemia, a major cause of neonatal death and pediatric disability.
9	23658158	The highly unusual sequence specificity of the nNOS:NOS1AP interaction and involvement in excitotoxic signaling may provide future opportunities for generation of neuroprotectants with high specificity.
10	23658158	The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death.
11	23658158	Excitotoxic stimulus induces recruitment of NOS1AP to nNOS in rat cortical neuron culture.
12	23658158	Excitotoxic activation of p38MAPK and subsequent neuronal death are reduced by competing with the nNOS:NOS1AP interaction and by knockdown with NOS1AP-targeting siRNAs.
13	23658158	We designed a cell-permeable peptide that competes for the unique PDZ domain of nNOS that interacts with NOS1AP.
14	23658158	This peptide inhibits NMDA-induced recruitment of NOS1AP to nNOS and in vivo in rat, doubles surviving tissue in a severe model of neonatal hypoxia-ischemia, a major cause of neonatal death and pediatric disability.
15	23658158	The highly unusual sequence specificity of the nNOS:NOS1AP interaction and involvement in excitotoxic signaling may provide future opportunities for generation of neuroprotectants with high specificity.
16	23658158	The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death.
17	23658158	Excitotoxic stimulus induces recruitment of NOS1AP to nNOS in rat cortical neuron culture.
18	23658158	Excitotoxic activation of p38MAPK and subsequent neuronal death are reduced by competing with the nNOS:NOS1AP interaction and by knockdown with NOS1AP-targeting siRNAs.
19	23658158	We designed a cell-permeable peptide that competes for the unique PDZ domain of nNOS that interacts with NOS1AP.
20	23658158	This peptide inhibits NMDA-induced recruitment of NOS1AP to nNOS and in vivo in rat, doubles surviving tissue in a severe model of neonatal hypoxia-ischemia, a major cause of neonatal death and pediatric disability.
21	23658158	The highly unusual sequence specificity of the nNOS:NOS1AP interaction and involvement in excitotoxic signaling may provide future opportunities for generation of neuroprotectants with high specificity.
22	23658158	The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death.
23	23658158	Excitotoxic stimulus induces recruitment of NOS1AP to nNOS in rat cortical neuron culture.
24	23658158	Excitotoxic activation of p38MAPK and subsequent neuronal death are reduced by competing with the nNOS:NOS1AP interaction and by knockdown with NOS1AP-targeting siRNAs.
25	23658158	We designed a cell-permeable peptide that competes for the unique PDZ domain of nNOS that interacts with NOS1AP.
26	23658158	This peptide inhibits NMDA-induced recruitment of NOS1AP to nNOS and in vivo in rat, doubles surviving tissue in a severe model of neonatal hypoxia-ischemia, a major cause of neonatal death and pediatric disability.
27	23658158	The highly unusual sequence specificity of the nNOS:NOS1AP interaction and involvement in excitotoxic signaling may provide future opportunities for generation of neuroprotectants with high specificity.
28	23658158	The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death.
29	23658158	Excitotoxic stimulus induces recruitment of NOS1AP to nNOS in rat cortical neuron culture.
30	23658158	Excitotoxic activation of p38MAPK and subsequent neuronal death are reduced by competing with the nNOS:NOS1AP interaction and by knockdown with NOS1AP-targeting siRNAs.
31	23658158	We designed a cell-permeable peptide that competes for the unique PDZ domain of nNOS that interacts with NOS1AP.
32	23658158	This peptide inhibits NMDA-induced recruitment of NOS1AP to nNOS and in vivo in rat, doubles surviving tissue in a severe model of neonatal hypoxia-ischemia, a major cause of neonatal death and pediatric disability.
33	23658158	The highly unusual sequence specificity of the nNOS:NOS1AP interaction and involvement in excitotoxic signaling may provide future opportunities for generation of neuroprotectants with high specificity.
34	23658158	The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death.
35	23658158	Excitotoxic stimulus induces recruitment of NOS1AP to nNOS in rat cortical neuron culture.
36	23658158	Excitotoxic activation of p38MAPK and subsequent neuronal death are reduced by competing with the nNOS:NOS1AP interaction and by knockdown with NOS1AP-targeting siRNAs.
37	23658158	We designed a cell-permeable peptide that competes for the unique PDZ domain of nNOS that interacts with NOS1AP.
38	23658158	This peptide inhibits NMDA-induced recruitment of NOS1AP to nNOS and in vivo in rat, doubles surviving tissue in a severe model of neonatal hypoxia-ischemia, a major cause of neonatal death and pediatric disability.
39	23658158	The highly unusual sequence specificity of the nNOS:NOS1AP interaction and involvement in excitotoxic signaling may provide future opportunities for generation of neuroprotectants with high specificity.