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Gene Information

Gene symbol: ORMDL3

Gene name: ORM1-like 3 (S. cerevisiae)

HGNC ID: 16038

Related Genes

# Gene Symbol Number of hits
1 GSDML 1 hits
2 ICOSLG 1 hits
3 IL10 1 hits
4 IL12B 1 hits
5 IL1R2 1 hits
6 IL23A 1 hits
7 IL23R 1 hits
8 JAK2 1 hits
9 NKX2-3 1 hits
10 REL 1 hits
11 SMAD3 1 hits
12 STAT3 1 hits
13 TYK2 1 hits
14 ZPBP2 1 hits

Related Sentences

# PMID Sentence
1 19732864 Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease.
2 19732864 Previous reports by us and others have linked the disease-associated genetic variants with changes in expression of GSDMB and ORMDL3 transcripts in human lymphoblastoid cell lines (LCLs).
3 19732864 Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease.
4 19732864 Previous reports by us and others have linked the disease-associated genetic variants with changes in expression of GSDMB and ORMDL3 transcripts in human lymphoblastoid cell lines (LCLs).
5 21300624 Amongst these are multiple genes involved in IL23/Th17 signalling (IL23R, IL12B, JAK2, TYK2 and STAT3), IL10, IL1R2, REL, CARD9, NKX2.3, ICOSLG, PRDM1, SMAD3 and ORMDL3.
6 21300624 For Crohn's disease, defective processing of intracellular bacteria has become a central theme, following gene discoveries in autophagy and innate immunity (associations with NOD2, IRGM, ATG16L1 are specific to Crohn's disease).
7 21300624 Genetic evidence has also demonstrated the importance of barrier function to the development of ulcerative colitis (HNF4A, LAMB1, CDH1 and GNA12).