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Gene Information
Gene symbol: OTP
Gene name: orthopedia homeobox
HGNC ID: 8518
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | POU3F2 | 1 hits |
| 2 | SIM1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11785508 | Of the four defective genes identified as primary in human holoprosencephaly, three exhibit a ventrodorsal gradient of expression (SHH, SIX3, and TGIF) and one a dorsoventral gradient (ZIC2). |
| 2 | 11785508 | Secondary down-regulation of the OTP gene or of downstream genes such as BRN2 or SIM1 may result in failure of terminal differentiation of magnocellular neurons of the supraoptic and paraventricular hypothalamic nuclei. |