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Gene Information
Gene symbol: PARP4
Gene name: poly (ADP-ribose) polymerase family, member 4
HGNC ID: 271
Synonyms: VAULT3, p193, VPARP, VWA5C
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
17430191
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To date, seven isoforms have been identified: PARP-1, PARP-2, PARP-3, PARP-4 (Vault-PARP), PARP-5 (Tankyrases), PARP-7 and PARP-10 with structural domains and different functions.
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2 |
17430191
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PARP-1, the best characterised member, works as a DNA damage nick-sensor protein that uses beta-NAD(+) to form polymers of ADP-ribose and has been implicated in DNA repair, maintenance of genomic integrity and mammalian longevity.
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