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Gene Information

Gene symbol: PDE7A

Gene name: phosphodiesterase 7A

HGNC ID: 8791

Synonyms: HCP1

Related Genes

# Gene Symbol Number of hits
1 MTFR1 1 hits
2 PDE10A 1 hits
3 PDE3B 1 hits
4 PDE4C 1 hits
5 PDE8A 1 hits

Related Sentences

# PMID Sentence
1 21152070 As shown by transgenic mouse models and by using phosphodiesterase 3 (PDE3) inhibitors, PDE3B has an important role in the regulation of insulin secretion in pancreatic β-cells.
2 21152070 Here, we show that PDE3B is activated in response to high glucose, insulin and cAMP elevation in rat pancreatic islets and INS-1 (832/13) cells.
3 21152070 In addition to PDE3B, several other PDEs were detected in human pancreatic islets: PDE1, PDE3, PDE4C, PDE7A, PDE8A and PDE10A.
4 22054870 This variant influences the expression of 2 adjacent genes, PDE7A and MTFR1, which are potential regulators of inflammation and oxidative injury, respectively.