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Gene Information

Gene symbol: PFKP

Gene name: phosphofructokinase, platelet

HGNC ID: 8878

Synonyms: PFK-C, PFKF

Related Genes

# Gene Symbol Number of hits
1 FTO 1 hits
2 INSIG2 1 hits
3 PFKL 1 hits
4 PITRM1 1 hits

Related Sentences

# PMID Sentence
1 8764833 The rat PFK-A amino-acid sequence is 69% and 68% identical to those for rat PFK-B and rat PFK-C, respectively, and differences in residues involved in binding of allosteric effectors were observed among the three isoforms.
2 8764833 Rat PFK-A expressed as a glutathione-S-transferase fusion protein was recognized by antibodies raised against a peptide in the PFK-A sequence.
3 8764833 Interleukin-1 impairs islet glucose metabolism and insulin secretion and was found to induce a specific decline in islet expression of PFK-A mRNA.
4 15919810 The phosphofructokinase (PFK) C (Pfkp) and the pitrilysin metalloprotease 1 (Pitrm1) genes are compelling positional candidate genes in this region that show coding sequence differences between the parental strains in functional domains.
5 17658951 Initial analysis suggested that several SNPs in the FTO and PFKP genes were associated with increased BMI, hip circumference, and weight.
6 18682847 Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes.