Ignet

Gene Information

Gene symbol: PHOX2B

Gene name: paired-like homeobox 2b

HGNC ID: 9143

Synonyms: Phox2b, NBPhox

Related Genes

#	Gene Symbol	Number of hits
1	CTGF	1 hits
2	G6PC	1 hits
3	INS	1 hits
4	NKX2-2	1 hits
5	SCN5A	1 hits

Related Sentences

#	PMID	Sentence
1	18506029	Downregulation of Phox2b shortly thereafter was dependent upon Nkx2.2 expressed in the adjacent pancreatic epithelium.
2	18506029	In Phox2b(-/-) embryos, neurons and glia did not develop in the pancreas, and Nkx2.2 expression was markedly upregulated in the epithelium.
3	18506029	In addition, the number and replication rate of insulin-expressing beta-cells increased in the Phox2b(-/-) mice.
4	18506029	We conclude that, during pancreatic development, Phox2b and Nkx2.2 form a non-cell-autonomous feedback loop that links the neural crest with the pancreatic epithelium, regulates the size of the beta-cell population, and thereby impacts insulin-secretory capacity and energy homeostasis.
5	18506029	Downregulation of Phox2b shortly thereafter was dependent upon Nkx2.2 expressed in the adjacent pancreatic epithelium.
6	18506029	In Phox2b(-/-) embryos, neurons and glia did not develop in the pancreas, and Nkx2.2 expression was markedly upregulated in the epithelium.
7	18506029	In addition, the number and replication rate of insulin-expressing beta-cells increased in the Phox2b(-/-) mice.
8	18506029	We conclude that, during pancreatic development, Phox2b and Nkx2.2 form a non-cell-autonomous feedback loop that links the neural crest with the pancreatic epithelium, regulates the size of the beta-cell population, and thereby impacts insulin-secretory capacity and energy homeostasis.
9	18506029	Downregulation of Phox2b shortly thereafter was dependent upon Nkx2.2 expressed in the adjacent pancreatic epithelium.
10	18506029	In Phox2b(-/-) embryos, neurons and glia did not develop in the pancreas, and Nkx2.2 expression was markedly upregulated in the epithelium.
11	18506029	In addition, the number and replication rate of insulin-expressing beta-cells increased in the Phox2b(-/-) mice.
12	18506029	We conclude that, during pancreatic development, Phox2b and Nkx2.2 form a non-cell-autonomous feedback loop that links the neural crest with the pancreatic epithelium, regulates the size of the beta-cell population, and thereby impacts insulin-secretory capacity and energy homeostasis.
13	18506029	Downregulation of Phox2b shortly thereafter was dependent upon Nkx2.2 expressed in the adjacent pancreatic epithelium.
14	18506029	In Phox2b(-/-) embryos, neurons and glia did not develop in the pancreas, and Nkx2.2 expression was markedly upregulated in the epithelium.
15	18506029	In addition, the number and replication rate of insulin-expressing beta-cells increased in the Phox2b(-/-) mice.
16	18506029	We conclude that, during pancreatic development, Phox2b and Nkx2.2 form a non-cell-autonomous feedback loop that links the neural crest with the pancreatic epithelium, regulates the size of the beta-cell population, and thereby impacts insulin-secretory capacity and energy homeostasis.
17	20004937	Post-mortem heart sections were immunohistochemically stained for collagen types I and III and connective tissue growth factor (CTGF).
18	20004937	Genomic DNA was prepared from post-mortem samples, and genetic analysis was performed in the SCN5A, G6PC, PHOX2B, and CTGF genes.
19	20004937	Twenty-two dead in bed syndrome cases were identified and staining of heart sections for collagen I and III, and CTGF showed no differences between dead in bed syndrome cases and controls.
20	20004937	No genetic variants were found in G6PC, PHOX2B, and CTGF, and dead in bed syndrome cases were not associated with the G-945C CTGF promoter polymorphism.
21	20004937	Post-mortem heart sections were immunohistochemically stained for collagen types I and III and connective tissue growth factor (CTGF).
22	20004937	Genomic DNA was prepared from post-mortem samples, and genetic analysis was performed in the SCN5A, G6PC, PHOX2B, and CTGF genes.
23	20004937	Twenty-two dead in bed syndrome cases were identified and staining of heart sections for collagen I and III, and CTGF showed no differences between dead in bed syndrome cases and controls.
24	20004937	No genetic variants were found in G6PC, PHOX2B, and CTGF, and dead in bed syndrome cases were not associated with the G-945C CTGF promoter polymorphism.