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Gene Information
Gene symbol: PIAS1
Gene name: protein inhibitor of activated STAT, 1
HGNC ID: 2752
Synonyms: GBP, GU/RH-II, ZMIZ3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GGH | 1 hits |
| 2 | MAPK7 | 1 hits |
| 3 | PGR | 1 hits |
| 4 | PIAS2 | 1 hits |
| 5 | PIAS4 | 1 hits |
| 6 | PLCB1 | 1 hits |
| 7 | RWDD1 | 1 hits |
| 8 | STAT1 | 1 hits |
| 9 | STAT2 | 1 hits |
| 10 | XBP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10480605 | Basal and stimulated levels of adenine and guanine nucleotides, the activation of phospholipase C by Ca2+ or glucose, the secretory response to pertussis toxin, and the activation of selected low-molecular weight GBPs were not impaired. |
| 2 | 18467627 | Effects of MEK5/ERK5 association on small ubiquitin-related modification of ERK5: implications for diabetic ventricular dysfunction after myocardial infarction. |
| 3 | 18467627 | ERK5 wild-type transcriptional activity was inhibited by Ubc9 (SUMO E2 conjugase) or PIAS1 (E3 ligase), but not in the ERK5-SUMOylation-site defective mutant (K6R/K22R). |
| 4 | 20408817 | In the present study we show that XBP1s, the active spliced form of XBP1 protein, is SUMOylated, mainly by PIAS2 [protein inhibitor of activated STAT (signal transducer and activator of transcription) 2] at two lysine residues located in the C-terminal transactivation domain. |
| 5 | 22406838 | RWDD1 interacts with the ligand binding domain of the androgen receptor and acts as a coactivator of androgen-dependent transactivation. |
| 6 | 22406838 | RWD domain containing 1 (RWDD1) was identified as an AR-interacting protein from three independent libraries of the embryonic days E15, E16 and E17. |
| 7 | 22539679 | Uterine production of leukemia inhibitory factor (LIF) and phosphorylation of uterine NFkappaBp65 and STAT3-Ty705 were found to be low (P < 0.01) during Day 4.5 postcoitum, whereas IFNgamma was aberrantly overexpressed. |
| 8 | 22539679 | Loss of temporal regulation of progesterone receptor A (PR A) and PR B, together with aberrantly increased expression of the protein inhibitor of activated STAT-y (PIASy) (P < 0.01) and reduced recruitment (P < 0.01) of the latter to nuclear progesterone receptor sites were prominent features of decidualization failure occurring at peri-implantation in dNOD mice. |