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Gene Information
Gene symbol: PIAS4
Gene name: protein inhibitor of activated STAT, 4
HGNC ID: 17002
Synonyms: Piasg, PIASY, FLJ12419, ZMIZ6
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | PGR | 1 hits |
| 3 | PIAS1 | 1 hits |
| 4 | PTPRN | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15596545 | Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells. |
| 2 | 15596545 | Islet cell autoantigen 512 (ICA512)/IA-2 is a receptor tyrosine phosphatase-like protein associated with the insulin secretory granules (SGs) of pancreatic beta-cells. |
| 3 | 15596545 | This cleavage occurs at the plasma membrane and generates an ICA512 cytosolic fragment that is targeted to the nucleus, where it binds the E3-SUMO ligase protein inhibitor of activated signal transducer and activator of transcription-y (PIASy) and up-regulates insulin expression. |
| 4 | 22539679 | Uterine production of leukemia inhibitory factor (LIF) and phosphorylation of uterine NFkappaBp65 and STAT3-Ty705 were found to be low (P < 0.01) during Day 4.5 postcoitum, whereas IFNgamma was aberrantly overexpressed. |
| 5 | 22539679 | Loss of temporal regulation of progesterone receptor A (PR A) and PR B, together with aberrantly increased expression of the protein inhibitor of activated STAT-y (PIASy) (P < 0.01) and reduced recruitment (P < 0.01) of the latter to nuclear progesterone receptor sites were prominent features of decidualization failure occurring at peri-implantation in dNOD mice. |