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Gene Information

Gene symbol: PMAIP1

Gene name: phorbol-12-myristate-13-acetate-induced protein 1

HGNC ID: 9108

Synonyms: APR, NOXA

Related Genes

# Gene Symbol Number of hits
1 ATF3 1 hits
2 ATF4 1 hits
3 BAK1 1 hits
4 BAX 1 hits
5 BBC3 1 hits
6 BCL2 1 hits
7 BCL2L1 1 hits
8 BCL2L11 1 hits
9 HIST1H2AA 1 hits
10 HIST2H2AC 1 hits
11 MCL1 1 hits
12 TNFRSF10A 1 hits
13 TNFRSF10B 1 hits
14 TNFSF10 1 hits
15 TP53 1 hits

Related Sentences

# PMID Sentence
1 17569614 Resveratrol induces apoptosis by up-regulating the expression of Bax, Bak, PUMA, Noxa, Bim, p53, TRAIL, TRAIL-R1/DR4 and TRAIL-R2/DR5 and simultaneously down-regulating the expression of Bcl-2, Bcl-XL, Mcl-1 and survivin.
2 17569614 Resveratrol causes growth arrest at G1 and G1/S phases of cell cycle by inducing the expression of CDK inhibitors p21/WAF1/CIP1 and p27/KIP1.
3 19164757 Like bortezomib, EerI-induced cytotoxicity requires the up-regulation of the Bcl-2 homology3 (BH3)-only pro-apoptotic protein NOXA.
4 19164757 First, these agents elicit an integrated stress response program at the ER to activate the CREB/ATF transcription factors ATF3 and ATF4.
5 19164757 We show that ATF3 and ATF4 form a complex capable of binding to the NOXA promoter, which is required for NOXA activation.
6 19164757 Second, EerI and bortezomib also block ubiquitination of histone H2A to relieve its inhibition on NOXA transcription.
7 19164757 Like bortezomib, EerI-induced cytotoxicity requires the up-regulation of the Bcl-2 homology3 (BH3)-only pro-apoptotic protein NOXA.
8 19164757 First, these agents elicit an integrated stress response program at the ER to activate the CREB/ATF transcription factors ATF3 and ATF4.
9 19164757 We show that ATF3 and ATF4 form a complex capable of binding to the NOXA promoter, which is required for NOXA activation.
10 19164757 Second, EerI and bortezomib also block ubiquitination of histone H2A to relieve its inhibition on NOXA transcription.
11 19164757 Like bortezomib, EerI-induced cytotoxicity requires the up-regulation of the Bcl-2 homology3 (BH3)-only pro-apoptotic protein NOXA.
12 19164757 First, these agents elicit an integrated stress response program at the ER to activate the CREB/ATF transcription factors ATF3 and ATF4.
13 19164757 We show that ATF3 and ATF4 form a complex capable of binding to the NOXA promoter, which is required for NOXA activation.
14 19164757 Second, EerI and bortezomib also block ubiquitination of histone H2A to relieve its inhibition on NOXA transcription.