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Gene Information
Gene symbol: PML
Gene name: promyelocytic leukemia
HGNC ID: 9113
Synonyms: MYL, TRIM19, RNF71
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AIRE | 1 hits |
| 2 | AVP | 1 hits |
| 3 | DYNC1H1 | 1 hits |
| 4 | FOXO1 | 1 hits |
| 5 | KLRG1 | 1 hits |
| 6 | NEUROD1 | 1 hits |
| 7 | RPS27A | 1 hits |
| 8 | SIRT1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 6590897 | [A case of acute promyelocytic leukemia associated with diabetes insipidus and chromosomal abnormality, t(8;17) (p22;q21)]. |
| 2 | 12595897 | Variable combinations of autoimmune endocrine diseases such as Addison's disease, hypoparathyroidism, and type 1 diabetes characterize APECED. |
| 3 | 12595897 | AIRE contains two PHD (plant homeodomain) type zinc fingers, four nuclear receptor binding LXXLL motifs, a putative DNA-binding domain named SAND and, in addition, a highly conserved N-terminal domain similar to the homogenously staining region domain of the Sp100 protein. |
| 4 | 12595897 | At the subcellular level, AIRE is expressed in nuclear dots resembling promyelocytic leukemia nuclear bodies, which are associated with several transcriptionally active proteins. |
| 5 | 16154098 | FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. |
| 6 | 16154098 | We show that the forkhead protein FoxO1 protects beta cells against oxidative stress by forming a complex with the promyelocytic leukemia protein Pml and the NAD-dependent deacetylase Sirt1 to activate expression of NeuroD and MafA, two Insulin2 (Ins2) gene transcription factors. |
| 7 | 16154098 | Using acetylation-defective and acetylation-mimicking mutants, we demonstrate that acetylation targets FoxO1 to Pml and prevents ubiquitin-dependent degradation. |
| 8 | 16154098 | We show that hyperglycemia suppresses MafA expression in vivo and that MafA inhibition can be prevented by transgenic expression of constitutively nuclear FoxO1 in beta cells. |
| 9 | 16154098 | FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. |
| 10 | 16154098 | We show that the forkhead protein FoxO1 protects beta cells against oxidative stress by forming a complex with the promyelocytic leukemia protein Pml and the NAD-dependent deacetylase Sirt1 to activate expression of NeuroD and MafA, two Insulin2 (Ins2) gene transcription factors. |
| 11 | 16154098 | Using acetylation-defective and acetylation-mimicking mutants, we demonstrate that acetylation targets FoxO1 to Pml and prevents ubiquitin-dependent degradation. |
| 12 | 16154098 | We show that hyperglycemia suppresses MafA expression in vivo and that MafA inhibition can be prevented by transgenic expression of constitutively nuclear FoxO1 in beta cells. |