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Gene Information
Gene symbol: POT1
Gene name: protection of telomeres 1 homolog (S. pombe)
HGNC ID: 17284
Synonyms: hPot1, DKFZp586D211
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | TPP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 23862686 | Akt regulates TPP1 homodimerization and telomere protection. |
| 2 | 23862686 | The phosphatidylinositol 3-kinase (PI3-K)/Akt (also known as PKB) pathway, one of the best characterized growth signaling cascades, regulates a variety of cellular function including cell proliferation, survival, metabolism, and DNA repair, and dysregulation of PI3-K/Akt signaling has been linked to aging and diseases such as cancer and diabetes. |
| 3 | 23862686 | Telomere damage and reduced TPP1 dimerization as a result of Akt inhibition was also accompanied by diminished recruitment of TPP1 and POT1 to the telomeres. |