Ignet

Gene Information

Gene symbol: PPIF

Gene name: peptidylprolyl isomerase F

HGNC ID: 9259

Synonyms: hCyP3, Cyp-D

Related Genes

#	Gene Symbol	Number of hits
1	BAX	1 hits
2	BCL2	1 hits
3	CASP3	1 hits
4	INS	1 hits
5	PPID	1 hits
6	PTPRU	1 hits
7	SLC25A4	1 hits
8	SLC25A6P1	1 hits
9	TFAM	1 hits

Related Sentences

#	PMID	Sentence
1	20479245	Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency.
2	20479245	Genetic ablation of the Ppif gene, encoding cyclophilin D, restored beta-cell mass and decreased TUNEL and complement complex labeling without affecting beta-cell proliferation.
3	20479245	In adult mice maintained on a high-fat diet, Ppif ablation normalized fasting glucose and glucose and insulin responses to acute glucose challenge.
4	20479245	Thus, cyclophilin D and the mitochondrial permeability transition are critical regulators of beta-cell death caused by Pdx1 insufficiency.
5	20479245	Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency.
6	20479245	Genetic ablation of the Ppif gene, encoding cyclophilin D, restored beta-cell mass and decreased TUNEL and complement complex labeling without affecting beta-cell proliferation.
7	20479245	In adult mice maintained on a high-fat diet, Ppif ablation normalized fasting glucose and glucose and insulin responses to acute glucose challenge.
8	20479245	Thus, cyclophilin D and the mitochondrial permeability transition are critical regulators of beta-cell death caused by Pdx1 insufficiency.
9	20654738	Voltage-dependent anion channel (VDAC), adenine nucleotide translocator (ANT), cyclophilin D (CypD), transcription factor A (Tfam), Bax, Bcl-2 contents, caspase-3 and -9 activities were determined.
10	20654738	Additionally, endurance training reverted the hyperglycemia-induced CypD elevation, attenuating decrease of ANT, VDAC and Tfam.
11	20654738	Moreover, training prevented the STZ-induced elevation in Bax, Bax-to-Bcl-2 ratio, caspase-3 and -9 and the increased Bcl-2.
12	20654738	Voltage-dependent anion channel (VDAC), adenine nucleotide translocator (ANT), cyclophilin D (CypD), transcription factor A (Tfam), Bax, Bcl-2 contents, caspase-3 and -9 activities were determined.
13	20654738	Additionally, endurance training reverted the hyperglycemia-induced CypD elevation, attenuating decrease of ANT, VDAC and Tfam.
14	20654738	Moreover, training prevented the STZ-induced elevation in Bax, Bax-to-Bcl-2 ratio, caspase-3 and -9 and the increased Bcl-2.
15	23063677	Levels of calcineurin activity and EPO-induced phosphorylation of Akt and ERK were similar in GK and Wistar, though cytosolic HSP70 level was 50% lower and mitochondrial HSP60 level was 60% higher in GK.
16	23063677	Interaction of cyclophilin D (CypD) with mitochondrial inorganic phosphate carrier (PiC), which sensitizes the mPTP, was enhanced in GK.
17	23596421	Cyclophilin D (CyP-D) plays an essential regulatory role in pore opening.
18	23596421	This review will discuss direct and indirect mechanisms underlying CyP-D interaction with a target protein of the mPTP complex.
19	23596421	Cyclophilin D (CyP-D) plays an essential regulatory role in pore opening.
20	23596421	This review will discuss direct and indirect mechanisms underlying CyP-D interaction with a target protein of the mPTP complex.