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Gene Information
Gene symbol: PROX1
Gene name: prospero homeobox 1
HGNC ID: 9459
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADCY5 | 1 hits |
| 2 | ATP1A2 | 1 hits |
| 3 | CRY2 | 1 hits |
| 4 | DGKB | 1 hits |
| 5 | FADS1 | 1 hits |
| 6 | GCK | 1 hits |
| 7 | GIPR | 1 hits |
| 8 | GLIS3 | 1 hits |
| 9 | HSD11B1 | 1 hits |
| 10 | IGF1 | 1 hits |
| 11 | INS | 1 hits |
| 12 | MADD | 1 hits |
| 13 | MBP | 1 hits |
| 14 | MTNR1B | 1 hits |
| 15 | SLC30A8 | 1 hits |
| 16 | TCF7L2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19470805 | Haplotype mapping reduced the critical region of the distal part of the QTL to 31 Mbp containing the potential candidates Nr1i3, Apoa2, Atp1a2, Prox1, and Hsd11b1. |
| 2 | 20081858 | These include nine loci newly associated with fasting glucose (in or near ADCY5, MADD, ADRA2A, CRY2, FADS1, GLIS3, SLC2A2, PROX1 and C2CD4B) and one influencing fasting insulin and HOMA-IR (near IGF1). |
| 3 | 20081858 | We also demonstrated association of ADCY5, PROX1, GCK, GCKR and DGKB-TMEM195 with type 2 diabetes. |
| 4 | 20185807 | Defects in insulin processing and insulin secretion were seen in glucose-raising allele carriers at TCF7L2, SCL30A8, GIPR, and C2CD4B. |
| 5 | 20185807 | Abnormalities in early insulin secretion were suggested in glucose-raising allele carriers at MTNR1B, GCK, FADS1, DGKB, and PROX1 (lower insulinogenic index; no association with proinsulin or insulin sensitivity). |
| 6 | 20185807 | Two loci previously associated with fasting insulin (GCKR and IGF1) were associated with OGTT-derived insulin sensitivity indices in a consistent direction. |
| 7 | 21103350 | Variants from GIPR, TCF7L2, DGKB, MADD, CRY2, GLIS3, PROX1, SLC30A8 and IGF1 are associated with glucose metabolism in the Chinese. |