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Gene Information
Gene symbol: PRSS2
Gene name: protease, serine, 2 (trypsin 2)
HGNC ID: 9483
Synonyms: TRY2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CFTR | 1 hits |
| 2 | CTRC | 1 hits |
| 3 | MMP8 | 1 hits |
| 4 | MMP9 | 1 hits |
| 5 | PRSS1 | 1 hits |
| 6 | SPINK1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17204147 | Other genes, such as the anionic trypsinogen (PRSS2), the serine protease inhibitor, Kazal type 1 (SPINK1) and the cystic fibrosis transmembrane conductance regulator (CFTR) have been found to be associated with chronic pancreatitis (idiopathic and hereditary) as well. |
| 2 | 18428024 | Urinary matrix metalloproteinase -8, -9, -14 and their regulators (TRY-1, TRY-2, TATI) in patients with diabetic nephropathy. |
| 3 | 18428024 | We studied the levels, molecular forms, and degree of activation of urinary MMP-8, -9, -14, trypsin-1 and -2, as well as tumor-associated trypsin inhibitor (TATI) of DNP patients and healthy controls. |
| 4 | 18428024 | Urinary samples were analyzed for MMPs by Western blotting and gelatin zymography and for trypsin-1, -2, and TATI by time-resolved immunofluorometric assays. |
| 5 | 18428024 | Total MMP-8 immunoreactivity, the proportion of active MMP-9, and gelatinolytic activity in urine were significantly higher in DNP patients than in controls. |
| 6 | 18428024 | MMP-8 and MMP-9 were found to form high molecular weight complexes in DNP urine. |
| 7 | 18428024 | Total immunoreactivity of soluble urinary MMP-14 and the levels of trypsin (TRY)-1 and TRY-2, but not of TATI, were also significantly increased in DNP. |
| 8 | 18428024 | Zymography, Western blotting, and immunofluorometric analysis of DNP urine showed a significant association especially between activation of MMP-9 as well as PMN-type MMP-8 and TRY-2. |
| 9 | 18428024 | Urinary matrix metalloproteinase -8, -9, -14 and their regulators (TRY-1, TRY-2, TATI) in patients with diabetic nephropathy. |
| 10 | 18428024 | We studied the levels, molecular forms, and degree of activation of urinary MMP-8, -9, -14, trypsin-1 and -2, as well as tumor-associated trypsin inhibitor (TATI) of DNP patients and healthy controls. |
| 11 | 18428024 | Urinary samples were analyzed for MMPs by Western blotting and gelatin zymography and for trypsin-1, -2, and TATI by time-resolved immunofluorometric assays. |
| 12 | 18428024 | Total MMP-8 immunoreactivity, the proportion of active MMP-9, and gelatinolytic activity in urine were significantly higher in DNP patients than in controls. |
| 13 | 18428024 | MMP-8 and MMP-9 were found to form high molecular weight complexes in DNP urine. |
| 14 | 18428024 | Total immunoreactivity of soluble urinary MMP-14 and the levels of trypsin (TRY)-1 and TRY-2, but not of TATI, were also significantly increased in DNP. |
| 15 | 18428024 | Zymography, Western blotting, and immunofluorometric analysis of DNP urine showed a significant association especially between activation of MMP-9 as well as PMN-type MMP-8 and TRY-2. |
| 16 | 18604651 | These include alterations in genes coding for trypsinogens, the most abundant digestive enzymes (PRSS1 and PRSS2), the trypsin inhibitor (SPINK1) and the trypsin-degrading enzyme, chymotrypsinogen C (CTRC). |
| 17 | 18604651 | Indeed, alterations in at least two genes, SPINK1 and CTRC, are strongly associated with TCP. |