Ignet

Gene Information

Gene symbol: PSMC3IP

Gene name: PSMC3 interacting protein

HGNC ID: 17928

Synonyms: TBPIP, GT198, HUMGT198A

Related Genes

#	Gene Symbol	Number of hits
1	DMC1	1 hits
2	MND1	1 hits
3	RAD51	1 hits

Related Sentences

#	PMID	Sentence
1	15834424	The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination.
2	15834424	Rad51 and Dmc1 recombinases are the major players in these processes.
3	15834424	Disruption of meiosis-specific HOP2 or MND1 genes leads to severe defects in homologous synapsis and an early-stage recombination failure resulting in sterility.
4	15834424	Here we show that mouse Hop2 can efficiently form D-loops, the first recombination intermediates, but this activity is abrogated upon association with Mnd1.
5	15834424	Furthermore, the Hop2-Mnd1 heterodimer physically interacts with Rad51 and Dmc1 recombinases and stimulates their activity up to 35-fold.
6	15834424	Our data reveal an interplay among Hop2, Mnd1 and Rad51 and Dmc1 in the formation of the first recombination intermediates during meiosis.
7	15834424	The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination.
8	15834424	Rad51 and Dmc1 recombinases are the major players in these processes.
9	15834424	Disruption of meiosis-specific HOP2 or MND1 genes leads to severe defects in homologous synapsis and an early-stage recombination failure resulting in sterility.
10	15834424	Here we show that mouse Hop2 can efficiently form D-loops, the first recombination intermediates, but this activity is abrogated upon association with Mnd1.
11	15834424	Furthermore, the Hop2-Mnd1 heterodimer physically interacts with Rad51 and Dmc1 recombinases and stimulates their activity up to 35-fold.
12	15834424	Our data reveal an interplay among Hop2, Mnd1 and Rad51 and Dmc1 in the formation of the first recombination intermediates during meiosis.
13	15834424	The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination.
14	15834424	Rad51 and Dmc1 recombinases are the major players in these processes.
15	15834424	Disruption of meiosis-specific HOP2 or MND1 genes leads to severe defects in homologous synapsis and an early-stage recombination failure resulting in sterility.
16	15834424	Here we show that mouse Hop2 can efficiently form D-loops, the first recombination intermediates, but this activity is abrogated upon association with Mnd1.
17	15834424	Furthermore, the Hop2-Mnd1 heterodimer physically interacts with Rad51 and Dmc1 recombinases and stimulates their activity up to 35-fold.
18	15834424	Our data reveal an interplay among Hop2, Mnd1 and Rad51 and Dmc1 in the formation of the first recombination intermediates during meiosis.
19	15834424	The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination.
20	15834424	Rad51 and Dmc1 recombinases are the major players in these processes.
21	15834424	Disruption of meiosis-specific HOP2 or MND1 genes leads to severe defects in homologous synapsis and an early-stage recombination failure resulting in sterility.
22	15834424	Here we show that mouse Hop2 can efficiently form D-loops, the first recombination intermediates, but this activity is abrogated upon association with Mnd1.
23	15834424	Furthermore, the Hop2-Mnd1 heterodimer physically interacts with Rad51 and Dmc1 recombinases and stimulates their activity up to 35-fold.
24	15834424	Our data reveal an interplay among Hop2, Mnd1 and Rad51 and Dmc1 in the formation of the first recombination intermediates during meiosis.
25	21112301	Hop2-Mnd1 is a meiotic recombination mediator that stimulates DNA strand invasion by both Dmc1 and Rad51.
26	21112301	The condensation of DNA is Hop2-Mnd1 concentration-dependent, reversible, and specific to the heterodimer, as neither Hop2 nor Mnd1 acting alone can facilitate this reaction.