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Gene Information
Gene symbol: PTPRO
Gene name: protein tyrosine phosphatase, receptor type, O
HGNC ID: 9678
Synonyms: PTPU2, GLEPP1, PTP-U2, PTP-oc, NPHS6
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACTN4 | 1 hits |
| 2 | APOL1 | 1 hits |
| 3 | EFNB2 | 1 hits |
| 4 | HIF1A | 1 hits |
| 5 | SYNPO | 1 hits |
| 6 | TCF21 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17003339 | In db/db mice at the normoalbuminuric stage, hypoxia-inducible factor-1alpha (HIF-1alpha), ephrin B2, glomerular epithelial protein 1, and Pod-1, which play key roles in glomerulogenesis, were already upregulated in parallel with an alteration of genes related to glucose metabolism, lipid metabolism, and oxidative stress. |
| 2 | 17003339 | Through pioglitazone treatment, gene expression of ephrin B2, Pod-1, actinin 4alpha, and DG1, as well as that of oxidative stress and lipid metabolism, was restored concomitant with attenuation of albuminuria. |
| 3 | 21997392 | Compared with normal glomeruli, fewer cells stained for APOL1 in FSGS and HIVAN glomeruli, even when expression of the podocyte markers GLEPP1 and synaptopodin appeared normal. |
| 4 | 21997392 | Unexpectedly, in both FSGS and HIVAN but not normal kidneys, the media of medium artery and arterioles contained a subset of α-smooth muscle actin-positive cells that stained for APOL1. |