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Gene Information
Gene symbol: REEP1
Gene name: receptor accessory protein 1
HGNC ID: 25786
Synonyms: FLJ13110, SPG31
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | RAB3A | 1 hits |
| 2 | REEP2 | 1 hits |
| 3 | RTP1 | 1 hits |
| 4 | RTP2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 7961732 | Rab3A effector domain peptides induce insulin exocytosis via a specific interaction with a cytosolic protein doublet. |
| 2 | 7961732 | We demonstrate here that Rab3A effector domain peptides specifically stimulated insulin exocytosis in electroporated insulin-secreting cells (K0.5 activation, 6-8 microM) in a Ca(2+)-independent manner, although in the presence of Ca2+ insulin exocytosis was further potentiated. |
| 3 | 7961732 | By using a 125I-radiolabeled photoactivated cross-linking Rab3A effector domain peptide, we identified a cytosolic protein doublet (REEP-1 and REEP-2), which specifically interacted with the Rab3A effector domain. |
| 4 | 7961732 | Competitive inhibition studies revealed this protein-protein interaction to be at a concentration equivalent to that required for Rab3A effector domain peptides to trigger insulin exocytosis (Ki, 6-8 microM). |
| 5 | 20943918 | In contrast to the observation that RTP1, RTP2, and REEP1 enhance function of olfactory receptors by promoting their transit to the cell surface, we found that REEP2 does not increase cell surface expression of sweet receptors but instead alters their spatial organization. |