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Gene Information
Gene symbol: RIT2
Gene name: Ras-like without CAAX 2
HGNC ID: 10017
Synonyms: RIBA
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CXADR | 1 hits |
| 2 | GCG | 1 hits |
| 3 | SNAP25 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9299498 | SNAP-25 is phosphorylated by glucose and GLP-1 in RIN 1046-38 cells. |
| 2 | 9299498 | At least 4 proteins of 18, 25, 35, and 46 kDa size were found to be tyrosine phosphorylated in the presence of glucose and an insulin secretagogue, glucagon-like peptide-1 (GLP-1). |
| 3 | 9299498 | The addition of glucose and GLP-1 to cells that were exposed to the tyrosine kinase inhibitor genistein resulted in a decrease in the extent of phosphorylation of the 18, 25, and 35 kDa proteins and a concomitant reduction in insulin secretion, whereas treatment with vanadate, a tyrosine phosphatase inhibitor, led to enhanced responses. |
| 4 | 9299498 | These results suggest that tyrosine phosphorylation of SNAP-25 may be involved in the regulation of insulin secretion in RIN 1046-38 cells. |
| 5 | 15649414 | Immunostaining for the Coxsackie-adenovirus-receptor (CAR) detected the protein on the free-floating RIN cell clusters, but not on the RINm5F cells cultured as a monolayer of beta-cells. |