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Gene Information
Gene symbol: RPA3
Gene name: replication protein A3, 14kDa
HGNC ID: 10291
Synonyms: REPA3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | RPA1 | 1 hits |
| 2 | RPA2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12509449 | In a yeast two-hybrid system based on reconstitution of Ras signaling, menin was found to interact with the 32-kDa subunit (RPA2) of replication protein A (RPA), a heterotrimeric protein required for DNA replication, recombination, and repair. |
| 2 | 12509449 | Menin bound preferentially in vitro to free RPA2 rather than the RPA heterotrimer or a subcomplex consisting of RPA2 bound to the 14-kDa subunit (RPA3). |
| 3 | 12509449 | However, the 70-kDa subunit (RPA1) was coprecipitated from HeLa cell extracts along with RPA2 by menin-specific antibodies, suggesting that menin binds to the RPA heterotrimer or a novel RPA1-RPA2-containing complex in vivo. |
| 4 | 12509449 | This finding was consistent with the extensive overlap in the nuclear localization patterns of endogenous menin, RPA2, and RPA1 observed by immunofluorescence. |