- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- BioSummarAI
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: RPS6KB3
Gene name: ribosomal protein S6 kinase, 70kDa, polypeptide 3
HGNC ID: 10438
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADRB2 | 1 hits |
| 2 | ADRB3 | 1 hits |
| 3 | AGT | 1 hits |
| 4 | ATP6V1B1 | 1 hits |
| 5 | FTO | 1 hits |
| 6 | GNAS | 1 hits |
| 7 | GNB3 | 1 hits |
| 8 | IL6R | 1 hits |
| 9 | INS | 1 hits |
| 10 | PCSK1 | 1 hits |
| 11 | UCP1 | 1 hits |
| 12 | UCP2 | 1 hits |
| 13 | UCP3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 2122450 | The dominant insulin-stimulated ribosomal protein S6 kinase activity was purified to near homogeneity from insulin-treated 32P-labeled rat H4 hepatoma cells and found to copurify with a 70-kDa 32P-labeled polypeptide. |
| 2 | 2122450 | Insulin treatment increases the 32P content of the immunoprecipitated 70-kDa S6 kinase polypeptide 3- to 4-fold over basal levels; 32P-labeled serine, some 32P-labeled threonine, but no 32P-labeled tyrosine are detected after partial acid hydrolysis. |
| 3 | 2122450 | The phosphatase 2A-deactivated 70-kDa S6 kinase is neither reactivated nor phosphorylated by partially purified insulin-stimulated microtubule-associated protein 2 kinase, in experiments where Xenopus S6 kinase II undergoes phosphorylation and partial reactivation. |
| 4 | 2122450 | Thus insulin activates the 70-kDa S6 kinase by promoting phosphorylation of specific serine/threonine residues on the enzyme polypeptide, probably through activating an as-yet-unidentified serine/threonine protein kinase distinct from microtubule-associated protein 2 kinase. |
| 5 | 19301222 | The C825T single nucleotide polymorphism (SNP) in the guanine nucleotide-binding protein, beta polypeptide 3 ( GNB3) gene gives rise to a splice variant, GNB3s that has enhanced G protein activation and signal transduction activity. |
| 6 | 19594364 | We genotyped 11 single nucleotide polymorphisms for 10 obesity candidate genes including adrenergic beta-2-receptor surface, adrenergic beta-3-receptor surface, angiotensinogen, fat mass and obesity associated gene, guanine nucleotide binding protein beta polypeptide 3 (GNB3), interleukin 6 receptor, proprotein convertase subtilisin/kexin type 1 (PCSK1), uncoupling protein 1, uncoupling protein 2, and uncoupling protein 3. |
| 7 | 19594364 | Single-locus analyses showed significant main effects of the GNB3 and PCSK1 genes on the risk of T2D among the nonobese group (p = 0.002 and 0.047, respectively). |
| 8 | 19594364 | Further, interactions involving GNB3 and PCSK1 were suggested among the nonobese population using the generalized multifactor dimensionality reduction method (p = 0.001). |
| 9 | 19594364 | In addition, interactions among angiotensinogen, fat mass and obesity associated gene, GNB3, and uncoupling protein 3 genes were found in a significant four-locus generalized multifactor dimensionality reduction model among the obese population (p = 0.001). |