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Gene Information
Gene symbol: SCN3A
Gene name: sodium channel, voltage-gated, type III, alpha subunit
HGNC ID: 10590
Synonyms: Nav1.3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BHLHB5 | 1 hits |
| 2 | OPRD1 | 1 hits |
| 3 | PRKCA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11489532 | Beta3, a novel auxiliary subunit for the voltage gated sodium channel is upregulated in sensory neurones following streptozocin induced diabetic neuropathy in rat. |
| 2 | 18579738 | Continuous delta-opioid receptor activation reduces neuronal voltage-gated sodium channel (NaV1.7) levels through activation of protein kinase C in painful diabetic neuropathy. |
| 3 | 18579738 | Vector-mediated enkephalin production in vivo prevented the increase in DRG Na(V)1.7 observed in PDN, an effect that correlated with inhibition of phosphorylation of p38 MAPK (mitogen-activated protein kinase) and protein kinase C (PKC). |
| 4 | 18579738 | The results of these studies suggest that activation of the presynaptic delta-opioid receptor by enkephalin prevents the increase in neuronal Na(V)1.7 in DRG through inhibition of PKC and p38. |