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Gene Information

Gene symbol: SEL1L

Gene name: sel-1 suppressor of lin-12-like (C. elegans)

HGNC ID: 10717

Synonyms: IBD2, SEL1L1

Related Genes

# Gene Symbol Number of hits
1 CXADR 1 hits
2 FBLIM1 1 hits
3 IDDM2 1 hits
4 INS 1 hits

Related Sentences

# PMID Sentence
1 12030374 Two cytosine-adenine (CA) repeats CAR/CAL and RepIN20 occur in the human SEL1L gene, which is regarded as a candidate gene for insulin-dependent diabetes mellitus (IDDM) and Grave's disease.
2 12030374 The average heterozygosity was 0.68 for CAR/CAL polymorphism and 0.85 for RepIN20.
3 12030374 The size of PCR fragments of CAR/CAL ranged from 207-225 bp and the most frequent allele was 207 bp (40.4%).
4 12030374 In the light of the highly polymorphic nature of both microsatellites and their intragenic location in SEL1L gene, we suggest that they could provide a means for linkage analysis to clarify the potential role of SEL1L in conferring susceptibility to IDDM or Grave's disease.
5 12030374 Two cytosine-adenine (CA) repeats CAR/CAL and RepIN20 occur in the human SEL1L gene, which is regarded as a candidate gene for insulin-dependent diabetes mellitus (IDDM) and Grave's disease.
6 12030374 The average heterozygosity was 0.68 for CAR/CAL polymorphism and 0.85 for RepIN20.
7 12030374 The size of PCR fragments of CAR/CAL ranged from 207-225 bp and the most frequent allele was 207 bp (40.4%).
8 12030374 In the light of the highly polymorphic nature of both microsatellites and their intragenic location in SEL1L gene, we suggest that they could provide a means for linkage analysis to clarify the potential role of SEL1L in conferring susceptibility to IDDM or Grave's disease.
9 21536682 Consequently, Sel1l(+/-) mice are severely glucose-intolerant and exhibit significantly retarded glucose-stimulated insulin secretion.