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Gene Information
Gene symbol: SERPINB5
Gene name: serpin peptidase inhibitor, clade B (ovalbumin), member 5
HGNC ID: 8949
Synonyms: maspin
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
12746779
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Among HIV-infected drug users, receipt of antiretroviral therapy (ART) for >1 year was also associated with diabetes (adjusted OR for receipt of ART without a protease inhibitor, 4.1 [95% CI, 1.1-15.5]; adjusted OR for receipt of ART including a protease inhibitor, 5.5 [95% CI, 1.5-20.4]).
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2 |
20505014
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RT-qPCR and proteome analysis of human islets incubated with 16.7 mM/l glucose revealed a significant decrease in pro-angiogenic factors including vascular endothelial growth factor (VEGF) mRNA by 20% and VEGF protein levels by 42% as well as additional proteins such as fibroblast growth factor-4 by 41%, MMP9 by 18%, monocyte chemoattractant protein-1 by 21%, and prolactin by 25%.
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3 |
20505014
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In contrast, we observed a 17% increase in thrombospondin-1 (TSP-1, listed as THBS1 in the HUGO database) and a 37% increase in angiotensinogen gene expression levels, but neither angiotensin-converting enzyme nor angiotensin II type 1 receptor gene expression was affected.
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4 |
20505014
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The amounts of anti-angiogenic proteins such as TSP-1 and serpin B5/maspin were also increased by 70 and 98% respectively as well as endostatin by 63%.
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