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Gene Information

Gene symbol: SERPING1

Gene name: serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

HGNC ID: 1228

Synonyms: C1IN, C1-INH, HAE1, HAE2

Related Genes

# Gene Symbol Number of hits
1 AGRN 1 hits
2 BST2 1 hits
3 C1R 1 hits
4 C1S 1 hits
5 CARHSP1 1 hits
6 CD81 1 hits
7 CHI3L1 1 hits
8 EPSTI1 1 hits
9 GBP2 1 hits
10 GPLD1 1 hits
11 IFITM1 1 hits
12 INS 1 hits
13 JAK3 1 hits
14 LGALS3 1 hits
15 LGALS3BP 1 hits
16 LGALS9 1 hits
17 MET 1 hits
18 MFGE8 1 hits
19 SERPINC1 1 hits
20 SLC6A11 1 hits
21 TGM2 1 hits
22 TIMP2 1 hits

Related Sentences

# PMID Sentence
1 1440521 Under conditions closely approximating those in vivo (100 mM sodium carbonate pH 7.3 with 0.9% NaCl, 37 degrees C), antithrombin III (AT III) and the C1 inhibitor (C1-INH) are inactivated by methylglyoxal (MG) with pseudofirst-order kinetics and second-order rate constants of 25.2 and 7.8 M-1 min-1, respectively.
2 6455647 Immune complex glomerulonephritis without lupic symptoms was discovered in one of the C1-INH deficient subjects, and in a girl of the same family the same deficiency was associated with an insulin-dependent diabetes of sudden onset.
3 18561091 Transcriptome studies of endometrial samples recovered during the pre-attachment period identified many interferon-stimulated genes, genes that are possibly involved in embryo-maternal immune modulation ( C1S, C1R, C4, SERPING1, UTMP, CD81, IFITM1, BST2), as well as genes affecting cell adhesion ( AGRN, CD81, LGALS3BP, LGALS9, GPLD1, MFGE8, and TGM2) and remodeling of the endometrium ( CLDN4, MEP1B, LGMN, MMP19, TIMP2, TGM2, MET, and EPSTI1).
4 19997081 This particular biomarker panel consisting of 14 genes (C1inh, C1s, Carhsp1, Chi3l1, Gat3, Gbp2, Hspb1, Icam1, Jak3, Kcne2, Lama5, Lgals3, Nppa, Timp1) can be used in diabetic retinopathy pharmacotherapeutic research, and the biomarker development process outlined here is applicable to drug development efforts for other diseases.