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PMID |
Sentence |
1 |
1540394
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Overexpression of pulmonary surfactant apoprotein A mRNA in alveolar type II cells and nonciliated bronchiolar (Clara) epithelial cells in streptozotocin-induced diabetic rats demonstrated by in situ hybridization.
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2 |
1540394
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The most abundant surfactant protein is termed surfactant apoprotein A (SP-A).
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3 |
1540394
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We have examined the expression and localization of SP-A mRNA in streptozotocin-induced diabetic rats by in situ hybridization using a specific rat cDNA probe.
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4 |
1540394
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Immunohistostaining of SP-A in diabetic lungs was weak in alveolar type II cells.
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5 |
1540394
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However, by autoradiographs of in situ hybridization, compared with the control lungs, a larger number of silver grains for the SP-A mRNA were shown in alveolar type II cells and also in some bronchiolar epithelial (Clara) cells from the diabetic lungs.
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6 |
1540394
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These results were confirmed by measurement of the SP-A content and by Northern blot analysis.
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7 |
1540394
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The present study demonstrates an overexpression of SP-A mRNA despite the ultrastructural changes in the endoplasmic reticulum of alveolar type II cells in the diabetic lungs, which will provide new information on the regulatory mechanism of SP-A gene expression.
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8 |
1540394
|
Overexpression of pulmonary surfactant apoprotein A mRNA in alveolar type II cells and nonciliated bronchiolar (Clara) epithelial cells in streptozotocin-induced diabetic rats demonstrated by in situ hybridization.
|
9 |
1540394
|
The most abundant surfactant protein is termed surfactant apoprotein A (SP-A).
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10 |
1540394
|
We have examined the expression and localization of SP-A mRNA in streptozotocin-induced diabetic rats by in situ hybridization using a specific rat cDNA probe.
|
11 |
1540394
|
Immunohistostaining of SP-A in diabetic lungs was weak in alveolar type II cells.
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12 |
1540394
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However, by autoradiographs of in situ hybridization, compared with the control lungs, a larger number of silver grains for the SP-A mRNA were shown in alveolar type II cells and also in some bronchiolar epithelial (Clara) cells from the diabetic lungs.
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13 |
1540394
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These results were confirmed by measurement of the SP-A content and by Northern blot analysis.
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14 |
1540394
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The present study demonstrates an overexpression of SP-A mRNA despite the ultrastructural changes in the endoplasmic reticulum of alveolar type II cells in the diabetic lungs, which will provide new information on the regulatory mechanism of SP-A gene expression.
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15 |
1540394
|
Overexpression of pulmonary surfactant apoprotein A mRNA in alveolar type II cells and nonciliated bronchiolar (Clara) epithelial cells in streptozotocin-induced diabetic rats demonstrated by in situ hybridization.
|
16 |
1540394
|
The most abundant surfactant protein is termed surfactant apoprotein A (SP-A).
|
17 |
1540394
|
We have examined the expression and localization of SP-A mRNA in streptozotocin-induced diabetic rats by in situ hybridization using a specific rat cDNA probe.
|
18 |
1540394
|
Immunohistostaining of SP-A in diabetic lungs was weak in alveolar type II cells.
|
19 |
1540394
|
However, by autoradiographs of in situ hybridization, compared with the control lungs, a larger number of silver grains for the SP-A mRNA were shown in alveolar type II cells and also in some bronchiolar epithelial (Clara) cells from the diabetic lungs.
|
20 |
1540394
|
These results were confirmed by measurement of the SP-A content and by Northern blot analysis.
|
21 |
1540394
|
The present study demonstrates an overexpression of SP-A mRNA despite the ultrastructural changes in the endoplasmic reticulum of alveolar type II cells in the diabetic lungs, which will provide new information on the regulatory mechanism of SP-A gene expression.
|
22 |
1540394
|
Overexpression of pulmonary surfactant apoprotein A mRNA in alveolar type II cells and nonciliated bronchiolar (Clara) epithelial cells in streptozotocin-induced diabetic rats demonstrated by in situ hybridization.
|
23 |
1540394
|
The most abundant surfactant protein is termed surfactant apoprotein A (SP-A).
|
24 |
1540394
|
We have examined the expression and localization of SP-A mRNA in streptozotocin-induced diabetic rats by in situ hybridization using a specific rat cDNA probe.
|
25 |
1540394
|
Immunohistostaining of SP-A in diabetic lungs was weak in alveolar type II cells.
|
26 |
1540394
|
However, by autoradiographs of in situ hybridization, compared with the control lungs, a larger number of silver grains for the SP-A mRNA were shown in alveolar type II cells and also in some bronchiolar epithelial (Clara) cells from the diabetic lungs.
|
27 |
1540394
|
These results were confirmed by measurement of the SP-A content and by Northern blot analysis.
|
28 |
1540394
|
The present study demonstrates an overexpression of SP-A mRNA despite the ultrastructural changes in the endoplasmic reticulum of alveolar type II cells in the diabetic lungs, which will provide new information on the regulatory mechanism of SP-A gene expression.
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29 |
1540394
|
Overexpression of pulmonary surfactant apoprotein A mRNA in alveolar type II cells and nonciliated bronchiolar (Clara) epithelial cells in streptozotocin-induced diabetic rats demonstrated by in situ hybridization.
|
30 |
1540394
|
The most abundant surfactant protein is termed surfactant apoprotein A (SP-A).
|
31 |
1540394
|
We have examined the expression and localization of SP-A mRNA in streptozotocin-induced diabetic rats by in situ hybridization using a specific rat cDNA probe.
|
32 |
1540394
|
Immunohistostaining of SP-A in diabetic lungs was weak in alveolar type II cells.
|
33 |
1540394
|
However, by autoradiographs of in situ hybridization, compared with the control lungs, a larger number of silver grains for the SP-A mRNA were shown in alveolar type II cells and also in some bronchiolar epithelial (Clara) cells from the diabetic lungs.
|
34 |
1540394
|
These results were confirmed by measurement of the SP-A content and by Northern blot analysis.
|
35 |
1540394
|
The present study demonstrates an overexpression of SP-A mRNA despite the ultrastructural changes in the endoplasmic reticulum of alveolar type II cells in the diabetic lungs, which will provide new information on the regulatory mechanism of SP-A gene expression.
|
36 |
1540394
|
Overexpression of pulmonary surfactant apoprotein A mRNA in alveolar type II cells and nonciliated bronchiolar (Clara) epithelial cells in streptozotocin-induced diabetic rats demonstrated by in situ hybridization.
|
37 |
1540394
|
The most abundant surfactant protein is termed surfactant apoprotein A (SP-A).
|
38 |
1540394
|
We have examined the expression and localization of SP-A mRNA in streptozotocin-induced diabetic rats by in situ hybridization using a specific rat cDNA probe.
|
39 |
1540394
|
Immunohistostaining of SP-A in diabetic lungs was weak in alveolar type II cells.
|
40 |
1540394
|
However, by autoradiographs of in situ hybridization, compared with the control lungs, a larger number of silver grains for the SP-A mRNA were shown in alveolar type II cells and also in some bronchiolar epithelial (Clara) cells from the diabetic lungs.
|
41 |
1540394
|
These results were confirmed by measurement of the SP-A content and by Northern blot analysis.
|
42 |
1540394
|
The present study demonstrates an overexpression of SP-A mRNA despite the ultrastructural changes in the endoplasmic reticulum of alveolar type II cells in the diabetic lungs, which will provide new information on the regulatory mechanism of SP-A gene expression.
|
43 |
1540394
|
Overexpression of pulmonary surfactant apoprotein A mRNA in alveolar type II cells and nonciliated bronchiolar (Clara) epithelial cells in streptozotocin-induced diabetic rats demonstrated by in situ hybridization.
|
44 |
1540394
|
The most abundant surfactant protein is termed surfactant apoprotein A (SP-A).
|
45 |
1540394
|
We have examined the expression and localization of SP-A mRNA in streptozotocin-induced diabetic rats by in situ hybridization using a specific rat cDNA probe.
|
46 |
1540394
|
Immunohistostaining of SP-A in diabetic lungs was weak in alveolar type II cells.
|
47 |
1540394
|
However, by autoradiographs of in situ hybridization, compared with the control lungs, a larger number of silver grains for the SP-A mRNA were shown in alveolar type II cells and also in some bronchiolar epithelial (Clara) cells from the diabetic lungs.
|
48 |
1540394
|
These results were confirmed by measurement of the SP-A content and by Northern blot analysis.
|
49 |
1540394
|
The present study demonstrates an overexpression of SP-A mRNA despite the ultrastructural changes in the endoplasmic reticulum of alveolar type II cells in the diabetic lungs, which will provide new information on the regulatory mechanism of SP-A gene expression.
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