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Gene Information
Gene symbol: SIX3
Gene name: SIX homeobox 3
HGNC ID: 10889
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GLI2 | 1 hits |
| 2 | PTCH1 | 1 hits |
| 3 | SHH | 1 hits |
| 4 | TDGF1 | 1 hits |
| 5 | TGIF1 | 1 hits |
| 6 | ZIC2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11785508 | Of the four defective genes identified as primary in human holoprosencephaly, three exhibit a ventrodorsal gradient of expression (SHH, SIX3, and TGIF) and one a dorsoventral gradient (ZIC2). |
| 2 | 11785508 | Secondary down-regulation of the OTP gene or of downstream genes such as BRN2 or SIM1 may result in failure of terminal differentiation of magnocellular neurons of the supraoptic and paraventricular hypothalamic nuclei. |
| 3 | 17274816 | To date, seven genes have been positively implicated in HPE: Sonic hedgehog (SHH), ZIC2, SIX3, TGIF, PTCH, GLI2 and TDGF1. |
| 4 | 17274816 | A molecular diagnosis can be performed by gene sequencing and allele quantification for the four main genes SHH, ZIC2, SIX3 and TGIF. |
| 5 | 17274816 | To date, seven genes have been positively implicated in HPE: Sonic hedgehog (SHH), ZIC2, SIX3, TGIF, PTCH, GLI2 and TDGF1. |
| 6 | 17274816 | A molecular diagnosis can be performed by gene sequencing and allele quantification for the four main genes SHH, ZIC2, SIX3 and TGIF. |