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Gene Information
Gene symbol: SLAMF1
Gene name: signaling lymphocytic activation molecule family member 1
HGNC ID: 10903
Synonyms: CD150
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | CD48 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | ERVK2 | 1 hits |
| 5 | GATA3 | 1 hits |
| 6 | IL10 | 1 hits |
| 7 | IL4 | 1 hits |
| 8 | SLAMF6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17237411 | In this study, we report the production and characterization of a NOD.Nkrp1(b).Nkt1(b) congenic mouse strain, apply microarray expression analyses to limit candidate genes within the 95% confidence region, identify Slamf1 (encoding signaling lymphocyte activation molecule) and Slamf6 (encoding Ly108) as potential candidates, and demonstrate retarded signaling lymphocyte activation molecule expression during T cell development of NOD mice, resulting in reduced expression at the CD4(+)CD8(+) stage, which is consistent with decreased NKT cell production and deranged tolerance induction in NOD mice. |
| 2 | 18606638 | Impaired SLAM-SLAM homotypic interaction between invariant NKT cells and dendritic cells affects differentiation of IL-4/IL-10-secreting NKT2 cells in nonobese diabetic mice. |
| 3 | 18606638 | The regulatory function of invariant NKT (iNKT) cells for tolerance induction and prevention of autoimmunity is linked to a specific cytokine profile that comprises the secretion of type 2 cytokines like IL-4 and IL-10 (NKT2 cytokine profile). |
| 4 | 18606638 | In contrast, mature NOD mDC express significantly lower levels of SLAM and are unable to promote GATA-3 (the SLAM-induced intracellular signal) up-regulation and IL-4/IL-10 production in iNKT cells from NOD or C57BL/6 mice. |
| 5 | 18617371 | We measured polymorphisms in a human endogenous retrovirus, Herv K-18, which is located in the CD48 signaling lymphocyte activating (SLAM) gene on chromosome 1. |
| 6 | 18617371 | Lower levels of association were found in other polymorphisms located in the 3'untranslated region of Herv K-18 and in adjacent loci in CD48. |