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Gene Information
Gene symbol: SLC22A5
Gene name: solute carrier family 22 (organic cation/carnitine transporter), member 5
HGNC ID: 10969
Synonyms: OCTN2, SCD
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | PADI4 | 1 hits |
| 3 | PDCD1 | 1 hits |
| 4 | PTPN22 | 1 hits |
| 5 | SLC22A1 | 1 hits |
| 6 | SLC22A4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 7792634 | The mean FBS score of SCD patients was comparable with those of insulin dependent diabetics, but significantly higher than that of non-insulin dependent diabetics. |
| 2 | 15883854 | Several multiple, large-scale, genetic studies on autoimmune-disease-associated SNPs have been reported recently: peptidylarginine deiminase type 4 (PADI4) in rheumatoid arthritis (RA); solute carrier family 22 members 4 and 5 (SLC22A4 and 5) in RA and Crohn's disease (CD); programmed cell death 1 (PDCD1) in systemic lupus erythematosus (SLE), type 1 diabetes mellitus (T1D), and RA; and protein tyrosine phosphatase nonreceptor type 22 (PTPN22) in T1D, RA, and SLE. |
| 3 | 15883854 | Although SNPs in PADI4 had similar allele frequency among three groups [maximal difference 11%; (P >0.05)], the other three loci revealed statistically significant allele frequency differences (maximal difference 39% (P <0.00001), 13% (P <0.00001), and 8% (P <0.00001) in SLC22A4, PDCD1, and PTPN22, respectively). |
| 4 | 16796743 | Evidence for the association of the SLC22A4 and SLC22A5 genes with type 1 diabetes: a case control study. |
| 5 | 23771822 | OCTN1 and OCTN2 are associated with several pathologies, such as inflammatory bowel disease, primary carnitine deficiency, diabetes, neurological disorders, and cancer, thus representing useful pharmacological targets. |