Ignet
Search (e.g., vaccine, IFNG): Help
About
Home
Introduction
Statistics
Programs
Dignet
Gene
GenePair
BioSummarAI
Help & Docs
Documents
Help
FAQs
Links
Acknowledge
Disclaimer
Contact Us
UM Logo

UMMS Logo

UMMS Logo

Gene Information

Gene symbol: SLC25A27

Gene name: solute carrier family 25, member 27

HGNC ID: 21065

Synonyms: UCP4, FLJ33552

Related Genes

# Gene Symbol Number of hits
1 SLC25A14 1 hits
2 UCP1 1 hits
3 UCP2 1 hits
4 UCP3 1 hits

Related Sentences

# PMID Sentence
1 11929192 Five proteins have been cloned, named UCP1, UCP2, UCP3, UCP4 and UCP5/BMCP1.
2 11929192 UCP1 is expressed uniquely in the brown adipose tissue, while UCP2 is widely distributed, UCP3 is mainly restricted to skeletal muscle and UCP4 and UCP5/BMCP1 expressed in the brain.
3 11929192 Five proteins have been cloned, named UCP1, UCP2, UCP3, UCP4 and UCP5/BMCP1.
4 11929192 UCP1 is expressed uniquely in the brown adipose tissue, while UCP2 is widely distributed, UCP3 is mainly restricted to skeletal muscle and UCP4 and UCP5/BMCP1 expressed in the brain.
5 19413708 The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes.
6 19413708 In mammals, more than five family members have been identified, including UCP1, UCP2, UCP3, UCP4 (or BMCP1/UCP5) and UCP5.
7 19413708 The UCPs may play an important role in energy homeostasis and have become prominent in the fields of thermogenesis, obesity, diabetes and free-radical biology and have been considered candidate genes for obesity and insulin resistance.
8 19413708 This review summarizes data supporting the roles of UCP2 and UCP3 in energy dissipation, as well as the genetic variety association with fat metabolism, obesity and diabetes in humans.
9 23841103 The physiological functions of UCPs have long been debated since the new UCPs (UCP2 to 5) were discovered, and the role of UCPs in the pathogeneses of diabetes mellitus is one of the hottest topics.
10 23841103 UCP2 is expressed in several tissues and acts in the negative regulation of insulin secretion by β-cells and in fatty acid metabolism.
11 23841103 UCP3 plays a role in fatty acid metabolism and energy homeostasis and modulates insulin sensitivity.
12 23841103 Several gene polymorphisms of UCP1, UCP2, and UCP3 were reported to be associated with diabetes.
13 23841103 The progress in the role of UCP1, UCP2, and UCP3 on diabetes mellitus is summarized in this review.