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Gene Information
Gene symbol: SLC35A2
Gene name: solute carrier family 35 (UDP-galactose transporter), member A2
HGNC ID: 11022
Synonyms: UGAT, UGT, UGT1, UGT2, UGTL
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CYP3A4 | 1 hits |
| 2 | PHF5A | 1 hits |
| 3 | SLC45A2 | 1 hits |
| 4 | SULT1A1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12399156 | The activities examined were cytochrome P450 (CYP) isoform activities (CYP2A6, CYP2D6, CYP2C19, CYP1A2, CYP2E1, CYP3A4 and CYP2C9) and phase 2 conjugation enzyme activities (phenol sulfotransferase (PST) and glucuronyl transferase (UGT)). |
| 2 | 12399156 | However, when three enzyme activities ((CYP3A4 x UGT)/PST) were taken into account, a correlation was made (r(2)=0.53). |
| 3 | 12399156 | Based on the correlation, we hypothesize that TRO and TRO sulfate are direct acting toxicants, whereas CYP3A4 oxidation and glucuronidation are detoxification pathways. |
| 4 | 22101373 | Non-nucleoside reverse transcriptase inhibitors (NNRTIs) or protease inhibitors (PIs), the current first line regimens of HAART, are metabolized by the cytochrome P450 family (CYP3A4). |
| 5 | 22101373 | Of interest, integrase inhibitors (INIs) - novel, potent anti-HIV drugs - are mainly metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1 and do not induce or inhibit CYP3A4. |