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Gene Information
Gene symbol: SP100
Gene name: SP100 nuclear antigen
HGNC ID: 11206
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AIRE | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12595897 | Variable combinations of autoimmune endocrine diseases such as Addison's disease, hypoparathyroidism, and type 1 diabetes characterize APECED. |
| 2 | 12595897 | AIRE contains two PHD (plant homeodomain) type zinc fingers, four nuclear receptor binding LXXLL motifs, a putative DNA-binding domain named SAND and, in addition, a highly conserved N-terminal domain similar to the homogenously staining region domain of the Sp100 protein. |
| 3 | 12595897 | At the subcellular level, AIRE is expressed in nuclear dots resembling promyelocytic leukemia nuclear bodies, which are associated with several transcriptionally active proteins. |