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Gene Information
Gene symbol: SPG21
Gene name: spastic paraplegia 21 (autosomal recessive, Mast syndrome)
HGNC ID: 20373
Synonyms: ACP33, GL010, BM-019, MAST
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | CIT | 1 hits |
| 3 | DMPK | 1 hits |
| 4 | PDK1 | 1 hits |
| 5 | PKN1 | 1 hits |
| 6 | PLK3 | 1 hits |
| 7 | PRKX | 1 hits |
| 8 | PRKY | 1 hits |
| 9 | RPS6KA1 | 1 hits |
| 10 | RPS6KB1 | 1 hits |
| 11 | SGK1 | 1 hits |
| 12 | SNF1LK | 1 hits |
| 13 | STK38 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20027184 | The family comprises some intensely examined protein kinases (such as Akt, S6K, RSK, MSK, PDK1 and GRK) as well as many less well-studied enzymes (such as SGK, NDR, LATS, CRIK, SGK494, PRKX, PRKY and MAST). |
| 2 | 23524293 | The group of AGC protein kinases includes more than 60 protein kinases in the human genome, classified into 14 families: PDK1, AKT/PKB, SGK, PKA, PKG, PKC, PKN/PRK, RSK, NDR, MAST, YANK, DMPK, GRK and SGK494. |
| 3 | 23524293 | This site is also essential to the mechanism of activation of AGC kinases by phosphorylation and is involved in the allosteric regulation of N-terminal domains of several AGC kinases, such as PKN/PRKs and atypical PKCs. |